SCHEMBL25014156

SCHEMBL25014156

O=P1(Oc2ccc(-c3ccccc3)cc2)OCC(CBr)(CBr)CO1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARG P37231 8/20 0.33
PPARA Q07869 6/20 0.33
PTGER4 P35408 1/20 0.33
GSTP1 P09211 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
LSS P48449 1/20 0.32
PTPN1 P18031 1/20 0.32
GSK3B P49841 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
HPGD P15428 2/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13816563 0.91 MAPK1 (0.35) POLBHTT
SCHEMBL21096821 0.83 CA1 (0.36) PTGER4NPC1RAB9ACA1CA2
SCHEMBL25014155 0.82 ALOX5 (0.40) PPARGPPARANPC1RAB9ACA1
SCHEMBL4145479 0.81 HSD17B10 (0.37) PTGER4NPC1RAB9ACA1CA2
SCHEMBL13816566 0.81 ALDH1A1 (0.30) ALDH1A1
SCHEMBL13697356 0.79 RAB9A (0.34) PPARGPPARANPC1RAB9ALSS
SCHEMBL25014160 0.75 TSHR (0.34) CA1CA2CA9POLBHTT
SCHEMBL25014899 0.74 CYP3A4 (0.34) HPGDPOLBHTTALDH1A1LMNA
SCHEMBL12669990 0.73 RECQL (0.41) POLBHTT
SCHEMBL25014158 0.72 SMN1; SMN2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023007982-A1 PHOSPHORUS COMPOUND HAVING ISOCYANURATE RING, SYNTHETIC METHOD THEREFOR, AND USE OF SAID PHOSPHORUS COMPOUND HAVING ISOCYANURATE RING 四国化成工業株式会社 2023-02-02 WO disclosed