SCHEMBL13697353

SCHEMBL13697353

CC1(C)COP(=O)(Oc2ccc3ccccc3c2)OC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
HSD17B10 Q99714 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
ALOX5 P09917 2/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
TDP1 Q9NUW8 3/20 0.34
KMT2A Q03164 2/20 0.34
AGXT P21549 1/20 0.34
PTPN7 P35236 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8745424 0.84 MAPK1 (0.33) HSD17B10CYP1A2MAPK1
SCHEMBL28060712 0.83 CYP1A2 (0.42) ALDH1A1HSD17B10HPGDALOX15CYP1A2
SCHEMBL3674965 0.82 MAPK1 (0.44) HSD17B10CYP1A2KMT2AMEN1L3MBTL1
SCHEMBL25014155 0.81 ALOX5 (0.40) ALDH1A1HSD17B10HPGDALOX15CYP1A2
SCHEMBL8761862 0.80 GAA (0.36) ALDH1A1HPGDCYP1A2TDP1KMT2A
SCHEMBL4145479 0.80 HSD17B10 (0.37) HSD17B10ALOX15CYP1A2CA1CA2
SCHEMBL13697355 0.79 EPHX1 (0.37) HSD17B10MAPK1
SCHEMBL13697354 0.78 CETP (0.38) ALDH1A1HSD17B10HPGDALOX15CYP1A2
SCHEMBL8761873 0.78 CYP3A4 (0.46) HSD17B10CYP1A2CA1CA2CA9
SCHEMBL13697357 0.75 ALDH1A1 (0.38) ALDH1A1HSD17B10HPGDTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105829466-B Flame-retardant coating agent for vehicle seat and method for producing flame-retardant vehicle seat material 日华化学株式会社 2018-11-23 CN disclosed
CN-108178943-A The manufacturing method of vehicular seats anti-flammability smears and anti-flammability seat material 日华化学株式会社 2018-06-19 CN disclosed
CN-105829466-A Flame-retardant coating agent for vehicle seat and method for producing flame-retardant vehicle seat material 日华化学株式会社 2016-08-03 CN disclosed
US-8835541-B2 Phosphorus compounds, use thereof and flame retarding polyester fibers DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2014-09-16 US disclosed
US-8835541-B2 Phosphorus compounds, use thereof and flame retarding polyester fibers DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2014-09-16 US disclosed
EP-1925622-B1 PHOSPHORUS COMPOUND, USE THEREOF AND FLAME-RETARDANT POLYESTER FIBER DAIHACHI CHEM IND (JP) 2013-10-16 EP disclosed
US-20090227713-A1 PHOSPHORUS COMPOUNDS, USE THEREOF AND FLAME RETARDING POLYESTER FIBERS DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-09-10 US disclosed
US-20090227713-A1 PHOSPHORUS COMPOUNDS, USE THEREOF AND FLAME RETARDING POLYESTER FIBERS DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2009-09-10 US disclosed
EP-1925622-A1 PHOSPHORUS COMPOUND, USE THEREOF AND FLAME-RETARDANT POLYESTER FIBER DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2008-05-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227713-A1 PHOSPHORUS COMPOUNDS, USE THEREOF AND FLAME RETARDING POLYESTER FIBERS POLL, FGFR1, FGFR4 ALDH1A1 2177/4885HSD17B10 1852/4885HPGD 3775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.