SCHEMBL250150

SCHEMBL250150

C(=Cc1cccc(-c2nc3ccccc3o2)c1-c1nc2ccccc2o1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 1/20 0.46
ALDH1A1 P00352 6/20 0.44
HPGD P15428 5/20 0.44
KDM4E B2RXH2 5/20 0.44
MAPT P10636 5/20 0.44
USP2 O75604 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
PTGS2 P35354 2/20 0.42
NPC1 O15118 6/20 0.42
TP53 P04637 5/20 0.42
RAB9A P51151 5/20 0.42
HSD17B10 Q99714 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
PKM P14618 2/20 0.42
GAA P10253 2/20 0.42
GLA P06280 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
KDM6B O15054 1/20 0.42
KDM6A O15550 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19717967 1.00 TOP2A (0.46) TOP2AALDH1A1HPGDKDM4EMAPT
SCHEMBL3213381 0.92 TP53 (0.43) TOP2AALDH1A1HPGDKDM4EMAPT
SCHEMBL11447096 0.92 TOP2A (0.44) TOP2AALDH1A1HPGDKDM4EMAPT
SCHEMBL285168 0.89 ALDH1A1 (0.48) TOP2AALDH1A1HPGDKDM4EMAPT
SCHEMBL28887970 0.89 ALDH1A1 (0.48) TOP2AALDH1A1HPGDKDM4EMAPT
SCHEMBL285170 0.89 ALDH1A1 (0.48) TOP2AALDH1A1HPGDKDM4EMAPT
SCHEMBL11458764 0.86 ALDH1A1 (0.46) TOP2AALDH1A1HPGDKDM4EMAPT
SCHEMBL11447095 0.86 ALDH1A1 (0.46) TOP2AALDH1A1HPGDKDM4EMAPT
SCHEMBL447889 0.85 RAB9A (0.53) ALDH1A1HPGDKDM4EMAPTTDP1
SCHEMBL6688218 0.82 MAPT (0.46) TOP2AALDH1A1HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116806243-B Polyolefin-based diffuser for lighting fixtures 哈维尔印度有限公司 2024-10-15 CN claimed
CN-116806243-A Polyolefin-based diffuser for lighting fixtures 哈维尔印度有限公司 2023-09-26 CN claimed
WO-2023139596-A1 POLYOLEFIN BASED DIFFUSER FOR LIGHTING FIXTURES HAVELLS INDIA LIMITED (IN) 2023-07-27 WO claimed
US-20230236350-A1 POLYOLEFIN BASED DIFFUSER FOR LIGHTING FIXTURES HAVELLS INDIA LIMITED (IN) 2023-07-27 US claimed
US-11597788-B2 Light curable composition HENKEL AG & CO. KGAA (DE) 2023-03-07 US claimed
US-11441013-B2 Method to adjust the elongation required to effect a color change in polymeric stretch films incorporating mechanochromic dyes DOW GLOBAL TECHNOLOGIES LLC (US) 2022-09-13 US claimed
CN-109789682-B Polyolefin-based stretched film incorporating mechanochromic dye and method of use thereof 陶氏环球技术有限责任公司 2021-12-21 CN claimed
EP-3380331-B1 PRINTED WATERMARK OMYA INT AG (CH) 2021-08-18 EP claimed
EP-3519185-B1 POLYOLEFIN BASED STRETCHED FILMS INCORPORATING MECHANOCHROMIC DYES AND METHOD TO USE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-08-04 EP claimed
US-20210221978-A1 A METHOD TO ADJUST THE ELONGATION REQUIRED TO EFFECT A COLOR CHANGE IN POLYMERIC STRETCH FILMS INCORPORATING MECHANOCHROMIC DYES DOW GLOBAL TECHNOLOGIES LLC 2021-07-22 US claimed
US-20060093762-A1 Masterbatch FELIX SCHOELLER JR. FOTO- UND SPEZIALPAPIERE GMBH & CO. KG (DE) 2006-05-04 US claimed
EP-1392901-A4 ULTRA WHITE WIPE BKI HOLDING CORP (US) 2005-03-16 EP claimed
US-20040121135-A1 ULTRA WHITE WIPE BKI HOLDING CORPORATION (US) 2004-06-24 US claimed
EP-1392901-A1 ULTRA WHITE WIPE BKI Holding Corporation (US) 2004-03-03 EP claimed
WO-2003087448-A1 ULTRA WHITE WIPE BKI HOLDING CORPORATION (US) 2003-10-23 WO claimed
US-5817448-A PYRAZOLINE OR BIS/BENZOXAZOLYL/ NAPHTHALENE, THIOPHENE OR STILBENE BASED BRIGHTENER FUJI PHOTO FILM CO., LTD. (JP) 1998-10-06 US claimed
US-5714310-A Photographic support comprising a resin layer containing TiO2 pigments being coated with an alkaline earth metal-containing compound MITSUBISHI PAPER MILLS LIMITED (JP) 1998-02-03 US claimed
US-5173397-A Sharpness of printed images, whiteness, surface properties MITSUBISHI PAPER MILLS LIMITED (JP) 1992-12-22 US claimed
US-5075206-A Fluorescent dye; brightness MITSUBISHI PAPER MILLS LIMITED (JP) 1991-12-24 US claimed
EP-0220576-B1 STAINPROOF POLYESTER FIBER TEIJIN LIMITED (JP) 1991-01-02 EP claimed