SCHEMBL25015137

SCHEMBL25015137

C=CC(=O)OCCOc1ccc(C#Cc2ccc(SCCSc3ccc(C#Cc4ccc(OCCOC(=O)C=C)c(C)c4)cc3)cc2)cc1C

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
PPARD Q03181 9/20 0.43
PPARA Q07869 1/20 0.43
ALDH1A1 P00352 5/20 0.36
MAPT P10636 4/20 0.36
HPGD P15428 4/20 0.36
ACACB O00763 1/20 0.35
FDPS P14324 1/20 0.34
LMNA P02545 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
TP53 P04637 2/20 0.33
TSHR P16473 2/20 0.33
HIF1A Q16665 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25015302 0.87 PPARD (0.42) THRBPPARDPPARAALDH1A1MAPT
SCHEMBL24806734 0.84 THRB (0.43) THRBPPARDPPARAALDH1A1HPGD
SCHEMBL24806608 0.83 THRB (0.37) THRBPPARDPPARAALDH1A1MAPT
SCHEMBL25015140 0.82 HPGD (0.39) THRBPPARDPPARAALDH1A1MAPT
SCHEMBL3102174 0.81 THRB (0.48) THRBPPARDPPARAALDH1A1MAPT
SCHEMBL24802623 0.80 FFAR4 (0.43) THRBACACB
SCHEMBL22862351 0.80 FFAR4 (0.43) THRBACACB
SCHEMBL24809371 0.80 TSHR (0.39) THRBPPARDPPARAALDH1A1HPGD
SCHEMBL24808445 0.78 THRB (0.34) THRBPPARDPPARAHPGDTSHR
SCHEMBL21615728 0.78 THRB (0.42) THRBALDH1A1MAPTLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230042009-A1 COMPOUND, COMPOSITION, CURED SUBSTANCE, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT FUJIFILM CORPORATION (JP) 2023-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230042009-A1 COMPOUND, COMPOSITION, CURED SUBSTANCE, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT SP1, C5, ZYX THRB 4220/4885PPARD 4531/4885PPARA 3308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.