Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 8/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39813 | 0.85 | THRB (0.51) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL3100741 | 0.84 | THRB (0.48) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL14173098 | 0.82 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL14173095 | 0.81 | THRB (0.48) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL25015137 | 0.81 | THRB (0.43) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL14173099 | 0.80 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL4953774 | 0.80 | PPARD (0.38) | THRBALDH1A1PPARDPPARALMNA | |
| SCHEMBL1828411 | 0.79 | THRB (0.62) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL14173241 | 0.78 | THRB (0.71) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL3102899 | 0.78 | THRB (0.71) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799844-B2 | Active energy beam-curable composition for optical material | TOAGOSEI CO., LTD. (JP) | 2010-09-21 | — | — | US | claimed |
| US-20070043143-A1 | Active energy beam-curable composition for optical material | THOMSON LICENSING (FR) | 2007-02-22 | — | — | US | claimed |
| US-7799844-B2 | Active energy beam-curable composition for optical material | TOAGOSEI CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20070043143-A1 | Active energy beam-curable composition for optical material | THOMSON LICENSING (FR) | 2007-02-22 | — | — | US | disclosed |