SCHEMBL25015302

SCHEMBL25015302

C=CC(=O)OCCSc1ccc(C#Cc2ccc(COc3ccc(C#Cc4ccc(SCCOC(=O)C=C)cc4)cc3C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 10/20 0.42
PPARA Q07869 2/20 0.42
MRGPRX4 Q96LA9 2/20 0.39
FFAR4 Q5NUL3 3/20 0.38
ACACB O00763 2/20 0.37
THRB P10828 1/20 0.35
FFAR1 O14842 1/20 0.35
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25015612 0.90 MAPT (0.40) PPARAMRGPRX4ACACBALDH1A1MAPT
SCHEMBL24802624 0.88 LMNA (0.35) PPARDPPARAMRGPRX4FFAR4ACACB
SCHEMBL25015137 0.87 THRB (0.43) PPARDPPARAACACBTHRBALDH1A1
SCHEMBL22862351 0.87 FFAR4 (0.43) MRGPRX4FFAR4ACACBTHRBFFAR1
SCHEMBL24802623 0.87 FFAR4 (0.43) MRGPRX4FFAR4ACACBTHRBFFAR1
SCHEMBL24803616 0.87 MAPT (0.37) FFAR4ACACBALDH1A1MAPTHPGD
SCHEMBL25014949 0.87 MAPT (0.37) FFAR4ACACBALDH1A1MAPTHPGD
SCHEMBL25015619 0.86 XDH (0.37) MRGPRX4FFAR4FFAR1
SCHEMBL25015617 0.84 ACACB (0.36) PPARDPPARAMRGPRX4FFAR4ACACB
SCHEMBL24806608 0.84 THRB (0.37) PPARDPPARAACACBTHRBFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230229038-A1 LIQUID CRYSTAL DIFFRACTION ELEMENT, OPTICAL ELEMENT, IMAGE DISPLAY UNIT, HEAD-MOUNTED DISPLAY, BEAM STEERING, AND SENSOR FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed
US-20230204968-A1 IMAGE DISPLAY UNIT AND HEAD-MOUNTED DISPLAY FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-20230205044-A1 LIQUID CRYSTAL DIFFRACTION ELEMENT, OPTICAL ELEMENT, IMAGE DISPLAY UNIT, HEAD-MOUNTED DISPLAY, BEAM STEERING, AND SENSOR FUJIFILM CORPORATION (JP) 2023-06-29 US disclosed
US-20230042009-A1 COMPOUND, COMPOSITION, CURED SUBSTANCE, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT FUJIFILM CORPORATION (JP) 2023-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230042009-A1 COMPOUND, COMPOSITION, CURED SUBSTANCE, OPTICALLY ANISOTROPIC BODY, OPTICAL ELEMENT, AND LIGHT GUIDE ELEMENT SP1, C5, ZYX PPARD 4531/4885PPARA 3308/4885MRGPRX4 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.