Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28633894 | 0.79 | KDM6B (0.47) | GAAALDH1A1 | |
| SCHEMBL25015506 | 0.78 | POLB (0.38) | LMNARAB9AGAASMN1; SMN2HPGD | |
| SCHEMBL9196900 | 0.77 | TDP1 (0.33) | — | |
| SCHEMBL29299999 | 0.76 | KDM4E (0.40) | LMNARAB9AHPGDALDH1A1 | |
| SCHEMBL9568028 | 0.75 | — | — | |
| SCHEMBL5440240 | 0.74 | CA12 (0.51) | GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28103048 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2 | |
| SCHEMBL19022027 | 0.72 | LMNA (0.36) | LMNARAB9AGAASMN1; SMN2HPGD | |
| SCHEMBL18592788 | 0.72 | RAB9A (0.40) | RXFP1LMNARAB9AGAASMN1; SMN2 | |
| SCHEMBL29910189 | 0.72 | ZDHHC20 (0.44) | GAATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023011639-A1 | OLIGOSACCHARIDE LINKER AND SIDE-CHAIN HYDROPHILIC FRAGMENT COMBINED GLYCOSITE-SPECIFIC ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2023-02-09 | — | — | WO | disclosed |