Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25017933 | 0.83 | ST14 (0.48) | PRSS1PRSS2PRSS3ST14F10 | |
| SCHEMBL25017951 | 0.83 | ST14 (0.48) | PRSS1PRSS2PRSS3ST14F10 | |
| SCHEMBL25016018 | 0.78 | HTR4 (0.46) | TPSAB1 | |
| SCHEMBL25016195 | 0.77 | F10 (0.45) | PRSS1PRSS2PRSS3ST14F10 | |
| SCHEMBL25016287 | 0.77 | F10 (0.45) | PRSS1PRSS2PRSS3ST14F10 | |
| SCHEMBL25017917 | 0.74 | ST14 (0.49) | PRSS1PRSS2PRSS3ST14F10 | |
| SCHEMBL25016058 | 0.73 | ST14 (0.41) | PRSS1PRSS2PRSS3ST14F10 | |
| SCHEMBL21489902 | 0.72 | CHRNA7 (0.56) | SMYD3CNR2 | |
| SCHEMBL19701326 | 0.72 | CHRNA7 (0.56) | SMYD3CNR2 | |
| SCHEMBL25017145 | 0.70 | F10 (0.46) | F10F2DRD4CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | MMP7, MATR3, SPINT2 | PRSS1 39/4885PRSS2 26/4885PRSS3 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.