Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 8/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 7/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | PLG | P00747 | 3/20 | 0.43 |
| ▸ | KLK1 | P06870 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.43 |
| ▸ | PLAT | P00750 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822442 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRF10PLA2G10PLAU | |
| SCHEMBL31689665 | 0.81 | ALDH1A1 (0.52) | ALDH1A1TSHRF10PLA2G10PLAU | |
| SCHEMBL25017213 | 0.80 | ALDH1A1 (0.45) | ALDH1A1TSHRF10PLA2G10PLAU | |
| SCHEMBL25017127 | 0.79 | ST14 (0.45) | F10F2PRSS1 | |
| SCHEMBL21822481 | 0.78 | PLA2G10 (0.46) | ALDH1A1TSHRPLA2G10FDPSDAO | |
| SCHEMBL31689651 | 0.78 | PLA2G10 (0.46) | ALDH1A1TSHRPLA2G10FDPSDAO | |
| SCHEMBL21822223 | 0.78 | F10 (0.53) | F10PLA2G10F2FDPSMCL1 | |
| SCHEMBL31689685 | 0.78 | F10 (0.53) | F10PLA2G10F2FDPSMCL1 | |
| SCHEMBL28583328 | 0.75 | F10 (0.38) | F10PLAUF2PLGPRSS1 | |
| SCHEMBL28583330 | 0.75 | F10 (0.38) | F10PLAUF2PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230043159-A1 | MATRIPTASE 2 INHIBITORS AND USES THEREOF | MMP7, MATR3, SPINT2 | ALDH1A1 3877/4885TSHR 4421/4885F10 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.