Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 7/20 | 0.51 |
| ▸ | PLG | P00747 | 3/20 | 0.51 |
| ▸ | KLK1 | P06870 | 3/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PLA2G10 | O15496 | 5/20 | 0.50 |
| ▸ | PLAT | P00750 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822442 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRPLAUPLGKLK1 | |
| SCHEMBL25017213 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TSHRPLAUPLGKLK1 | |
| SCHEMBL5247396 | 0.82 | ALDH1A1 (0.76) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL25016783 | 0.81 | ALDH1A1 (0.45) | ALDH1A1TSHRPLAUPLGKLK1 | |
| SCHEMBL25017933 | 0.79 | ST14 (0.48) | F2PRSS1F10 | |
| SCHEMBL25017951 | 0.79 | ST14 (0.48) | F2PRSS1F10 | |
| SCHEMBL28588636 | 0.78 | ALDH1A1 (0.42) | ALDH1A1TSHRPLA2G10DAOMCL1 | |
| SCHEMBL25017563 | 0.77 | F10 (0.60) | F2PRSS1PLA2G10F10 | |
| SCHEMBL21822542 | 0.76 | HTR4 (0.44) | PLGF2PRSS1F10 | |
| SCHEMBL21822179 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TSHRPLAUPLGF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428415-B2 | Matriptase 2 inhibitors and uses thereof | DISC MEDICINE, INC. (US) | 2025-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12428415-B2 | Matriptase 2 inhibitors and uses thereof | MMP7, MATR3, SPINT2 | ALDH1A1 3877/4885TSHR 4421/4885PLAU 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.