Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | NQO2 | P16083 | 4/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51330 | 0.74 | CRHBP (0.61) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL9813311 | 0.74 | MAPT (0.50) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL232685 | 0.74 | POLB (0.58) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL9229574 | 0.74 | MAPT (0.50) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL29359446 | 0.74 | CRHBP (0.61) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL17187704 | 0.74 | MAPT (0.50) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL8165959 | 0.70 | BLM (0.53) | MAPTALDH1A1HPGDGLAACHE | |
| Hydrochloric Acid SCHEMBL14871697 | 0.70 | MAPT (0.46) | MAPTALDH1A1HPGDGLAACHE | |
| SCHEMBL1264191 | 0.70 | MAPT (0.46) | MAPTALDH1A1HPGDGLAACHE | |
| Phenazine SCHEMBL182948 | 0.70 | MAPT (0.85) | MAPTALDH1A1HPGDGLAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637658-B2 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130123475-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | Life Technologies Corporation (US) | 2013-05-16 | — | — | US | disclosed |
| US-20120220751-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | Life Technologies Corporation (US) | 2012-08-30 | — | — | US | disclosed |
| US-20110245462-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | Life Technologies Corporation (US) | 2011-10-06 | — | — | US | disclosed |
| US-20090105452-A1 | NON-FLUORESCENT QUENCHER COMPOUNDS AND BIOMOLECULAR ASSAYS | APPLERA CORPORATION (US) | 2009-04-23 | — | — | US | disclosed |
| US-20050164225-A1 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC | 2005-07-28 | — | — | US | disclosed |
| US-20040005607-A1 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC | 2004-01-08 | — | — | US | disclosed |
| US-20030082547-A1 | Non-fluorescent quencher compounds and biomolecular assays | APPLIED BIOSYSTEMS, LLC | 2003-05-01 | — | — | US | disclosed |
| WO-2003019145-A2 | NON-FLUORESCENT QUENCHER COMPOUNDS AND BIOMOLECULAR ASSAYS | APPLERA CORPORATION (US) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164225-A1 | Non-fluorescent quencher compounds and biomolecular assays | DNTT, PNP, NT5C2 | MAPT 4274/4885ALDH1A1 3999/4885HPGD 2875/4885 |
| US-20130123475-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | DNTT, PNP, NT5C2 | MAPT 4230/4885ALDH1A1 3969/4885HPGD 2805/4885 |
| US-20030082547-A1 | Non-fluorescent quencher compounds and biomolecular assays | DNTT, PNP, NT5C2 | MAPT 4380/4885ALDH1A1 3285/4885HPGD 2905/4885 |
| US-20090105452-A1 | NON-FLUORESCENT QUENCHER COMPOUNDS AND BIOMOLECULAR ASSAYS | DNTT, PNP, NT5C2 | MAPT 4230/4885ALDH1A1 3969/4885HPGD 2805/4885 |
| US-20040005607-A1 | Non-fluorescent quencher compounds and biomolecular assays | DNTT, PNP, NT5C2 | MAPT 4380/4885ALDH1A1 3285/4885HPGD 2905/4885 |
| US-20110245462-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | DNTT, PNP, NT5C2 | MAPT 4230/4885ALDH1A1 3969/4885HPGD 2805/4885 |
| US-20120220751-A1 | Non-Fluorescent Quencher Compounds and Biomolecular Assays | DNTT, PNP, NT5C2 | MAPT 4230/4885ALDH1A1 3969/4885HPGD 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.