SCHEMBL29359446

SCHEMBL29359446

[O-][n+]1c2ccccc2nc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.61
CRHR2 Q13324 1/20 0.61
KEAP1 Q14145 1/20 0.61
NFE2L2 Q16236 1/20 0.61
ATM Q13315 1/20 0.54
MAPT P10636 7/20 0.50
ALDH1A1 P00352 6/20 0.42
GAA P10253 2/20 0.42
HPGD P15428 4/20 0.42
GLA P06280 3/20 0.42
ACHE P22303 2/20 0.42
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
POLB P06746 4/20 0.41
CASP6 P55212 3/20 0.41
NPC1 O15118 2/20 0.41
MMP14 P50281 2/20 0.41
BLM P54132 2/20 0.41
APAF1 O14727 1/20 0.41
PABPC1 P11940 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51330 1.00 CRHBP (0.61) CRHBPCRHR2KEAP1NFE2L2ATM
SCHEMBL28532290 0.82 CRHBP (0.64) CRHBPCRHR2KEAP1NFE2L2ATM
SCHEMBL15780725 0.80 CRHBP (0.49) CRHBPCRHR2KEAP1NFE2L2ATM
SCHEMBL15010394 0.78 CRHBP (1.00) CRHBPCRHR2KEAP1NFE2L2ATM
SCHEMBL28519683 0.78 CRHBP (0.47) CRHBPCRHR2KEAP1NFE2L2ATM
SCHEMBL8687444 0.78 ACHE (0.53) CRHBPCRHR2KEAP1NFE2L2ATM
SCHEMBL8688658 0.78 ALDH1A1 (0.44) CRHBPCRHR2KEAP1NFE2L2ATM
SCHEMBL30380175 0.78 CRHBP (0.47) CRHBPCRHR2KEAP1NFE2L2ATM
SCHEMBL11531389 0.77 CRHBP (0.54) CRHBPCRHR2KEAP1NFE2L2MAPT
SCHEMBL7915668 0.77 CRHBP (0.46) CRHBPCRHR2KEAP1NFE2L2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-12616081-B2 High precision greenhouse seed and seedling treatment SYNGENTA CROP PROTECTION AG (CH) 2026-05-05 US disclosed
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 US disclosed
US-12446583-B2 Methods of pest control in soybean SYNGENTA CROP PROTECTION AG (CH) 2025-10-21 US disclosed
US-12376512-B2 Precision treatment and sowing or planting method and device SYNGENTA CROP PROTECTION AG (CH) 2025-08-05 US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
US-12295368-B2 Method for controlling hematophagous or sap-feeding arthropods BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSTIY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2025-05-13 US disclosed
US-12262710-B2 Fungicidal compounds SYNGENTA CROP PROTECTION AG (CH) 2025-04-01 US disclosed
EP-4017244-B1 APPARATUS AND METHOD FOR REDUCING DUST DEVELOPMENT IN PRECISION DRILL SOWING SYNGENTA CROP PROTECTION AG (CH) 2025-03-12 EP disclosed
US-11357231-B2 Insecticidal compounds based on isoxazoline derivatives SYNGENTA CROP PROTECTION LLC (US) 2022-06-14 US disclosed
EP-3606913-B1 MICROBIOCIDAL OXADIAZOLE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2022-04-27 EP disclosed
US-11291205-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-04-05 US disclosed
WO-2022058580-A1 MICROBIOCIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2022-03-24 WO disclosed
US-11266146-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-03-08 US disclosed
US-11259524-B2 Microbiocidal oxadiazole derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-03-01 US disclosed
US-11241011-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2022-02-08 US disclosed
EP-3941898-A1 FUNGICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2022-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11291205-B2 Microbiocidal picolinamide derivatives CASP2, CASP1, MSR1 CRHBP 2542/4885CRHR2 2038/4885KEAP1 2574/4885
US-12616081-B2 High precision greenhouse seed and seedling treatment DCX, MYB, CROCC CRHBP 4274/4885CRHR2 4323/4885KEAP1 2163/4885
US-11241011-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 CRHBP 4736/4885CRHR2 4800/4885KEAP1 736/4885
US-11266146-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 CRHBP 4736/4885CRHR2 4800/4885KEAP1 736/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 CRHBP 4748/4885CRHR2 4602/4885KEAP1 652/4885
US-11357231-B2 Insecticidal compounds based on isoxazoline derivatives CYP4X1, NPY4R, CASP3 CRHBP 4399/4885CRHR2 2284/4885KEAP1 934/4885
US-12295368-B2 Method for controlling hematophagous or sap-feeding arthropods KCNN1, KCNN2, KCNN3 CRHBP 1751/4885CRHR2 4265/4885KEAP1 1073/4885
US-12446583-B2 Methods of pest control in soybean BTF3, KEAP1, HAX1 CRHBP 3808/4885CRHR2 3205/4885KEAP1 2/4885
US-11259524-B2 Microbiocidal oxadiazole derivatives PRF1, NOX1, ARG1 CRHBP 4592/4885CRHR2 4574/4885KEAP1 1033/4885
US-12262710-B2 Fungicidal compounds CYP1B1, CYP51A1, CYP1A1 CRHBP 4748/4885CRHR2 4602/4885KEAP1 652/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.