SCHEMBL9229574

SCHEMBL9229574

Cl[n+]1c2ccccc2nc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
MAOA P21397 2/20 0.42
MAOB P27338 1/20 0.42
ALDH1A1 P00352 5/20 0.42
HPGD P15428 4/20 0.42
GLA P06280 3/20 0.42
ACHE P22303 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
NQO2 P16083 5/20 0.40
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
NPC1 O15118 4/20 0.37
POLB P06746 4/20 0.37
KMT2A Q03164 4/20 0.37
KDM4E B2RXH2 4/20 0.37
HSD17B10 Q99714 4/20 0.37
MEN1 O00255 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9813311 0.74 MAPT (0.50) MAPTMAOAMAOBALDH1A1HPGD
SCHEMBL232685 0.74 POLB (0.58) MAPTMAOAMAOBALDH1A1HPGD
SCHEMBL29359446 0.74 CRHBP (0.61) MAPTMAOAMAOBALDH1A1HPGD
SCHEMBL51330 0.74 CRHBP (0.61) MAPTMAOAMAOBALDH1A1HPGD
SCHEMBL17187704 0.74 MAPT (0.50) MAPTMAOAMAOBALDH1A1HPGD
SCHEMBL2501715 0.74 MAPT (0.50) MAPTMAOAMAOBALDH1A1HPGD
Hydrochloric Acid SCHEMBL14871697 0.70 MAPT (0.46) MAPTMAOAMAOBALDH1A1HPGD
SCHEMBL1264191 0.70 MAPT (0.46) MAPTMAOAMAOBALDH1A1HPGD
Phenazine SCHEMBL29356959 0.69 MAPT (1.00) MAPTMAOAMAOBALDH1A1HPGD
Phenazine SCHEMBL27643128 0.69 MAPT (1.00) MAPTMAOAMAOBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671393-A1 Monoaminophenazine leuco dyes and photothermographic materials containing same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-09-13 EP disclosed