Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19484847 | 0.76 | NLRP3 (0.48) | NLRP3TSHRALDH1A1TDP1 | |
| SCHEMBL19256216 | 0.76 | — | — | |
| SCHEMBL19485103 | 0.73 | TSHR (0.40) | NLRP3TSHRALDH1A1TDP1 | |
| SCHEMBL19418935 | 0.73 | TSHR (0.40) | NLRP3TSHRALDH1A1TDP1 | |
| SCHEMBL18950544 | 0.72 | — | — | |
| SCHEMBL18950486 | 0.72 | — | — | |
| SCHEMBL14325274 | 0.72 | — | — | |
| SCHEMBL19256218 | 0.72 | — | — | |
| SCHEMBL25761262 | 0.70 | TSHR (0.54) | NLRP3TSHR | |
| SCHEMBL26000881 | 0.69 | APP (0.36) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11577179-B2 | Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography | WATERS TECHNOLOGIES CORPORATION (US) | 2023-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11577179-B2 | Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography | SEPTIN9, PORCN, SPECC1L | NLRP3 2204/4885TSHR 4592/4885ALDH1A1 3766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.