Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 6/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25021945 | 0.92 | NOS2 (0.35) | NOS2NOS3NOS1OPRK1EPHX2 | |
| SCHEMBL25021304 | 0.88 | NOS2 (0.37) | NOS2NOS3NOS1OPRK1EPHX2 | |
| SCHEMBL24100557 | 0.85 | LMNA (0.44) | NOS2NOS3NOS1OPRK1EPHX2 | |
| SCHEMBL25021253 | 0.84 | LMNA (0.38) | NOS2NOS3NOS1OPRK1EPHX2 | |
| SCHEMBL24506989 | 0.84 | NOS2 (0.37) | NOS2NOS3NOS1OPRK1EPHX2 | |
| SCHEMBL24100754 | 0.84 | LMNA (0.38) | NOS2NOS3NOS1OPRK1EPHX2 | |
| SCHEMBL24101173 | 0.82 | MC4R (0.38) | NOS2NOS3NOS1OPRK1EPHX2 | |
| SCHEMBL24101006 | 0.82 | MC4R (0.38) | NOS2NOS3NOS1OPRK1EPHX2 | |
| SCHEMBL25021254 | 0.81 | NOS2 (0.35) | NOS2NOS3NOS1OPRK1EPHX2 | |
| SCHEMBL25021306 | 0.81 | MC4R (0.35) | NOS2NOS3NOS1OPRK1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3866931-B1 | COMPOUNDS CONTAINING DEUTERIUM | ONCOPEPTIDES AB (SE) | 2023-02-15 | — | — | EP | disclosed |