SCHEMBL25023933

SCHEMBL25023933

c1ccc(-c2ccc(-c3ccc4oc5cc(-c6nc(-c7ccccc7)nc(-c7ccc(-n8c9ccccc9c9ccccc98)cc7)n6)c6ccccc6c5c4c3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.37
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
PLA2G2A P14555 3/20 0.35
PLA2G4A P47712 3/20 0.35
PGR P06401 1/20 0.33
HDAC4 P56524 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
SIRT1 Q96EB6 1/20 0.33
GAA P10253 1/20 0.33
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
TBK1 Q9UHD2 1/20 0.32
PRKDC P78527 3/20 0.32
PLA2G10 O15496 1/20 0.32
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22174776 0.94 KDM4E (0.39) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL25024228 0.91 L3MBTL1 (0.37) L3MBTL1KDM4EATMPGRHDAC4
SCHEMBL29322978 0.90 PLA2G2A (0.37) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL23602471 0.90 SIRT2 (0.36) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL24623758 0.90 L3MBTL1 (0.44) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL17974249 0.90 L3MBTL1 (0.44) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL22174781 0.89 L3MBTL1 (0.38) L3MBTL1KDM4EATMSIRT2SIRT1
SCHEMBL22174462 0.89 KDM4E (0.36) L3MBTL1KDM4EATMSIRT2SIRT1
SCHEMBL22145856 0.88 PLA2G2A (0.36) L3MBTL1KDM4EATMPLA2G2APLA2G4A
SCHEMBL25023934 0.88 KDM4E (0.38) L3MBTL1KDM4EATMPRKDCMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230048456-A1 ORGANIC LIGHT-EMITTING ELEMENT AND COMPOSITION FOR ORGANIC MATERIAL LAYER THEREOF LT MATERIALS CO., LTD. (KR) 2023-02-16 US disclosed