SCHEMBL29322978

SCHEMBL29322978

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4oc5ccc(-c6ccc(-n7c8ccccc8c8ccccc87)cc6)cc5c34)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.37
PLA2G4A P47712 4/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
KDM4E B2RXH2 2/20 0.36
ATM Q13315 2/20 0.36
PLA2G10 O15496 1/20 0.36
PIM1 P11309 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
PIM3 Q86V86 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
HDAC4 P56524 1/20 0.33
PGR P06401 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
PRKDC P78527 1/20 0.32
GAA P10253 1/20 0.32
CHEK2 O96017 1/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17252528 0.98 PLA2G2A (0.36) PLA2G2APLA2G4AL3MBTL1KDM4EATM
SCHEMBL25944400 0.98 PLA2G2A (0.36) PLA2G2APLA2G4AL3MBTL1KDM4EATM
SCHEMBL22145856 0.98 PLA2G2A (0.36) PLA2G2APLA2G4AL3MBTL1KDM4EATM
SCHEMBL22329764 0.98 L3MBTL1 (0.38) PLA2G2APLA2G4AL3MBTL1KDM4EATM
SCHEMBL25944181 0.97 PLA2G2A (0.35) PLA2G2APLA2G4AL3MBTL1KDM4EATM
SCHEMBL19933674 0.97 L3MBTL1 (0.35) PLA2G2APLA2G4AL3MBTL1KDM4EATM
SCHEMBL22257568 0.96 PLA2G2A (0.35) PLA2G2APLA2G4AL3MBTL1KDM4EATM
SCHEMBL22257878 0.96 PLA2G2A (0.35) PLA2G2APLA2G4AL3MBTL1KDM4EATM
SCHEMBL29324426 0.96 PLA2G2A (0.34) PLA2G2APLA2G4AL3MBTL1KDM4EATM
SCHEMBL22257773 0.96 PLA2G2A (0.35) PLA2G2APLA2G4AL3MBTL1KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4401536-A1 ORGANIC LIGHT-EMITTING DEVICE LG Chem, Ltd. (KR) 2024-07-17 EP disclosed