SCHEMBL107882

SCHEMBL107882

Cc1cc(Cl)ccc1C(=O)Cl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.51
FLT4 P35916 1/20 0.51
KDR P35968 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.47
TSHR P16473 2/20 0.47
CASP1 P29466 1/20 0.47
CYP11B2 P19099 1/20 0.46
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MYC P01106 1/20 0.44
MAOB P27338 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43
ABL1 P00519 1/20 0.43
ALDH1A1 P00352 2/20 0.42
MAPK1 P28482 1/20 0.42
HIF1A Q16665 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250256 0.84 FLT1 (0.53) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL109654 0.83 SMN1; SMN2 (0.63) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL30628195 0.83 FLT1 (0.51) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL4574528 0.83 FLT1 (0.51) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL874097 0.83 ALDH1A1 (0.47) SMN1; SMN2TSHRCASP1RAB9ANPC1
SCHEMBL26019671 0.82 FLT1 (0.47) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL2010267 0.81 CYP2A6 (0.46) SMN1; SMN2RAB9ANPC1MAPTALDH1A1
SCHEMBL11255876 0.81 FLT1 (0.50) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL2468739 0.81 KDM4E (0.55) FLT1FLT4KDRSMN1; SMN2TSHR
SCHEMBL9555496 0.81 FLT1 (0.50) FLT1FLT4KDRSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250381182-A1 ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE AMYGDALA NEUROSCIENCES, INC. (US) 2025-12-18 US disclosed
US-12351569-B2 ALDH-2 inhibitor compounds and methods of use AMYGDALA NEUROSCIENCES, INC. (US) 2025-07-08 US disclosed
EP-4540237-A1 ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE Amygdala Neurosciences, Inc. (US) 2025-04-23 EP disclosed
US-12018009-B2 ALDH-2 inhibitor compounds and methods of use AMYGDALA NEUROSCIENCES, INC. (US) 2024-06-25 US disclosed
CN-117645607-A Electroluminescent material and application thereof 北京燕化集联光电技术有限公司 2024-03-05 CN disclosed
CN-117535046-A Luminescent material composition and application thereof 北京燕化集联光电技术有限公司 2024-02-09 CN disclosed
WO-2023244574-A1 ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE AMYGDALA NEUROSCIENCES, INC. (US) 2023-12-21 WO disclosed
US-20230399307-A1 ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE AMYGDALA NEUROSCIENCES, INC. (US) 2023-12-14 US disclosed
US-20230399315-A1 ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE AMYGDALA NEUROSCIENCES, INC. (US) 2023-12-14 US disclosed
US-11482684-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-10-25 US disclosed
WO-1999065897-A1 INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 CHIRON CORPORATION (US) 1999-12-23 WO disclosed
CN-1129952-A Detergent-package combination PROCTER & GAMBLE (US) 1996-08-28 CN disclosed
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed
US-4588715-A ASNTICHOLESTEROL AGENTS, ATHEROSCLEROSIS, SILYLPHENYL DERIVATIVES SANDOZ, INC. (US) 1986-05-13 US disclosed
US-4431797-A ELECTROLYTIC REDUCTION OF TEREPHTHALIC ACID TO AMMONIUM SALT OF P- STANDARD OIL COMPANY (INDIANA) (US) 1984-02-14 US disclosed
US-4182847-A Monomers for poly(methylenebenzoate) polymers from toluic acid compounds STANDARD OIL COMPANY (INDIANA) (US) 1980-01-08 US disclosed
US-4122116-A HERBICIDES DEUTSCHE GOLD- UND SILBER- SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-10-24 US disclosed
US-4108877-A REACTING ACYL HALIDE WITH COPPER CYANIDE WITH HEATING IN THE PRESENCE OF A CARBOXYLIC ACID NITRILE AND AN ORGANIC SOLVENT DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-08-22 US disclosed
US-4108875-A REACTING ACYL HALIDE WITH AN ALKALI METAL CYANIDE AND A COPPER(I) SALT IN THE PRESENCE OF A CARBOXYLIC ACID NITRILE WITH HEATING DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-08-22 US disclosed
US-4006009-A 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides VELSICOL CHEMICAL CORPORATION (US) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11482684-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OSBP FLT1 4782/4885FLT4 4450/4885KDR 3311/4885
US-20230399315-A1 ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE ALDH1A1, ALDH2, ALDH3A1 FLT1 4026/4885FLT4 4203/4885KDR 2180/4885
US-20230399307-A1 ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE ALDH1A1, ALDH2, ALDH3A1 FLT1 4028/4885FLT4 4208/4885KDR 2209/4885
US-20250381182-A1 ALDH-2 INHIBITOR COMPOUNDS AND METHODS OF USE ALDH1A1, ALDH2, ALDH3A1 FLT1 4026/4885FLT4 4203/4885KDR 2180/4885
US-12351569-B2 ALDH-2 inhibitor compounds and methods of use ALDH1A1, ALDH2, ALDH3A1 FLT1 4028/4885FLT4 4208/4885KDR 2209/4885
US-12018009-B2 ALDH-2 inhibitor compounds and methods of use ALDH1A1, ALDH2, ALDH3A1 FLT1 4026/4885FLT4 4203/4885KDR 2180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.