Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.75 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | AHR | P35869 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622065 | 1.00 | HSD17B1 (0.75) | HSD17B1HSD17B2ALDH1A1MAPTMEN1 | |
| SCHEMBL18415558 | 0.87 | ALDH1A1 (0.75) | ALDH1A1MAPTMEN1KMT2ACYP1A1 | |
| SCHEMBL3009193 | 0.86 | HSD17B1 (1.00) | HSD17B1HSD17B2ALDH1A1MAPTMEN1 | |
| SCHEMBL5833241 | 0.86 | ALDH1A1 (0.73) | ALDH1A1MAPTMEN1KMT2ACYP1A1 | |
| SCHEMBL11660515 | 0.86 | ALDH1A1 (0.73) | ALDH1A1MAPTMEN1PKMKMT2A | |
| SCHEMBL2502603 | 0.86 | MAPT (0.71) | HSD17B1HSD17B2ALDH1A1MAPTMEN1 | |
| SCHEMBL5657703 | 0.85 | ALDH1A1 (0.66) | HSD17B1HSD17B2ALDH1A1MAPTMEN1 | |
| SCHEMBL27860047 | 0.85 | HSD17B1 (0.58) | HSD17B1HSD17B2ALDH1A1MAPTMEN1 | |
| SCHEMBL30615269 | 0.84 | HSD17B1 (0.57) | HSD17B1HSD17B2ALDH1A1MAPTMEN1 | |
| SCHEMBL14384842 | 0.84 | MEN1 (0.62) | HSD17B1HSD17B2ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003176-A | Benzimidazoles compound and its application containing amide | 沈阳药科大学 | 2019-07-12 | — | — | CN | claimed |
| US-6903090-B2 | Such as 10-(2-ethoxyphenyl)-1,2,3,4,5,6-hexahydroazepino(4,5-b)indole; for treatment of anxiety, depression, schizophrenia, epilepsy, migraine, Alzheimers disease, sleep disorders, obesity, stress related diseases, and/or drug withdrawal | PFIZER (US) | 2005-06-07 | — | — | US | claimed |
| US-6828314-B2 | Modulation of the activity of serotonin receptors (5-HT) to treat diseases such as anxiety, depression or obesity | PFIZER | 2004-12-07 | — | — | US | claimed |
| US-20030225058-A1 | Substituted azepino[4,5b]indoline derivatives | PHARMACIA & UPJOHN COMPANY | 2003-12-04 | — | — | US | claimed |
| CN-117088864-A | Benzo [ d ] isoxazole compound and application thereof | 广州智药生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2023217063-A1 | BENZO[D]ISOXAZOLE COMPOUND AND USE THEREOF | 广州智药生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |
| US-20230157996-A1 | SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF | Shenzhen Bay Laboratory (CN) | 2023-05-25 | — | — | US | disclosed |
| CN-113651766-A | Isoxazole sulfonamide compound with BRD4 inhibitory activity and preparation method and application thereof | 泰州职业技术学院 | 2021-11-16 | — | — | CN | disclosed |
| CN-110003176-A | Benzimidazoles compound and its application containing amide | 沈阳药科大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-105085427-A | Benzo [ d ] isoxazole compound and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-11-25 | — | — | CN | disclosed |
| US-8426585-B2 | Compounds comprising a spiro-ring | Xi, Ning (US) | 2013-04-23 | — | — | US | disclosed |
| US-20110172203-A1 | Substituted Imidazopyridinyl-Aminopyridine Compounds | ARQULE, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |
| EP-0107780-B1 | FLUORAN COMPOUNDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 1987-11-04 | — | — | EP | disclosed |
| US-4600797-A | NITRATING AN AMINOBENZENE WHICH HAS A PROTECTEDD AMINO GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-15 | — | — | US | disclosed |
| US-4594601-A | Fluoran compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0107780-A2 | Fluoran compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 1984-05-09 | — | — | EP | disclosed |
| EP-0049711-B1 | PROCESS FOR THE PRODUCTION OF NITRO-AMINO-BENZENES | BAYER AG (DE) | 1984-02-29 | — | — | EP | disclosed |
| EP-0055218-A2 | Manufacture of azoic compounds | CIBA-GEIGY AG (CH) | 1982-06-30 | — | — | EP | disclosed |
| EP-0049711-A1 | Process for the production of nitro-amino-benzenes | BAYER AG (DE) | 1982-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230157996-A1 | SMALL-MOLECULE INHIBITOR TARGETING EB VIRUS NUCLEAR ANTIGEN PROTEIN, PREPARATION METHOD AND USE THEREOF | SSB, EBNA1BP2, PML | HSD17B1 3843/4885HSD17B2 4372/4885ALDH1A1 4846/4885 |
| US-20030225058-A1 | Substituted azepino[4,5b]indoline derivatives | HTR5A, HTR1A, HTR4 | HSD17B1 1375/4885HSD17B2 1297/4885ALDH1A1 734/4885 |
| US-20110172203-A1 | Substituted Imidazopyridinyl-Aminopyridine Compounds | MKI67, CDK4, ABL1 | HSD17B1 4283/4885HSD17B2 4233/4885ALDH1A1 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.