Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 7/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | WHR1 | P49842 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4137416 | 0.83 | OPRK1 (0.42) | SCN10AOPRK1PDE2A | |
| SCHEMBL25943482 | 0.82 | HRH3 (0.39) | OPRK1PDE2A | |
| SCHEMBL30412291 | 0.81 | SIGMAR1 (0.37) | SCN10ATRPV3SIGMAR1WHR1CYP11B1 | |
| SCHEMBL23623071 | 0.81 | PIK3CA (0.37) | SCN10ATRPV3SIGMAR1PIK3CAMTOR | |
| SCHEMBL24215698 | 0.81 | SIGMAR1 (0.37) | SCN10ATRPV3SIGMAR1WHR1CYP11B1 | |
| SCHEMBL24215208 | 0.81 | SCN10A (0.44) | SCN10AOPRK1TRPV3SIGMAR1CYP11B1 | |
| SCHEMBL26608320 | 0.79 | OPRK1 (0.53) | SCN10AOPRK1 | |
| SCHEMBL30593144 | 0.79 | OPRK1 (0.53) | SCN10AOPRK1 | |
| SCHEMBL12240380 | 0.79 | CHRNB2 (0.43) | — | |
| SCHEMBL19145279 | 0.79 | KDM4E (0.51) | OPRK1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018781-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2023-02-16 | — | — | WO | disclosed |