SCHEMBL250263

SCHEMBL250263

NC(=O)Nc1ccccc1N

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 15/20 0.64
HDAC1 Q13547 15/20 0.64
HDAC2 Q92769 15/20 0.64
MAPK1 P28482 1/20 0.64
HDAC6 Q9UBN7 9/20 0.60
HDAC10 Q969S8 8/20 0.60
HDAC8 Q9BY41 8/20 0.60
HDAC4 P56524 7/20 0.60
HDAC7 Q8WUI4 7/20 0.60
HDAC11 Q96DB2 7/20 0.60
HDAC9 Q9UKV0 7/20 0.60
HDAC5 Q9UQL6 7/20 0.60
NCOR2 Q9Y618 5/20 0.60
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
KDM4E B2RXH2 1/20 0.55
GAA P10253 1/20 0.55
PTGS1 P23219 2/20 0.53
GRIN2D O15399 1/20 0.49
GRIN3B O60391 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29840068 0.87 GAA (0.67) HDAC3HDAC1HDAC2MAPK1NPC1
SCHEMBL3928666 0.87 GAA (0.67) HDAC3HDAC1HDAC2MAPK1NPC1
SCHEMBL3071688 0.86 HDAC3 (0.64) HDAC3HDAC1HDAC2MAPK1HDAC6
SCHEMBL9515806 0.86 NPC1 (0.67) HDAC3HDAC1HDAC2MAPK1HDAC6
SCHEMBL31174164 0.86 HDAC3 (0.64) HDAC3HDAC1HDAC2MAPK1HDAC6
Benzylamine SCHEMBL7422652 0.85 HDAC1 (0.54) HDAC3HDAC1HDAC2MAPK1HDAC6
SCHEMBL6206535 0.85 GAA (0.55) HDAC3HDAC1HDAC2MAPK1HDAC6
SCHEMBL653241 0.84 HDAC3 (0.68) HDAC3HDAC1HDAC2MAPK1HDAC6
SCHEMBL24881745 0.82 HDAC3 (0.60) HDAC3HDAC1HDAC2MAPK1HDAC6
SCHEMBL21007304 0.82 HDAC1 (0.60) HDAC3HDAC1HDAC2MAPK1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264667-A High expansion rate silicone rubber cold shrink tube 任丘市恒威通信设备有限公司 2025-01-07 CN claimed
CN-117887283-A Preparation method of water-soluble yellow reactive dye 浙江劲光实业股份有限公司 2024-04-16 CN claimed
CN-110903679-A Green reactive dye based on monoazo structure of mono H acid and preparation and application thereof 东华大学 2020-03-24 CN claimed
CN-102796091-A Substituted oxazolidinone compound and preparation method and application thereof UNIV PEKING FOUNDER GROUP CO 2012-11-28 CN claimed
CN-1157617-A Heterobicyclic derivatives FUJISAWA PHARMACEUTICAL CO (JP) 1997-08-20 CN claimed
EP-0192242-B1 SUBSTITUTED AMINOPHENYLUREA DERIVATIVES TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1990-11-07 EP claimed
US-4803223-A ANTITUMOR AGENTS TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1989-02-07 US claimed
EP-0187121-B1 HEAT-CURABLE EPOXY RESIN COMPOSITIONS CIBA-GEIGY AG (CH) 1988-07-13 EP claimed
EP-0113609-B1 HEAT PROCESSABLE RECORDING ELEMENT AND DYE-FORMING PROCESSING SOLUTION FOR A PHOTOGRAPHIC SILVER HALIDE ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-06-08 EP claimed
US-4645818-A CONTAINING AN AMIDOARYLUREA CIBA-GEIGY CORPORATION (US) 1987-02-24 US claimed
EP-0192242-A1 Substituted aminophenylurea derivatives TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1986-08-27 EP claimed
EP-0113609-A2 Heat processable recording element and dye-forming processing solution for a photographic silver halide element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-07-18 EP claimed
US-4426441-A PHOTOTHERMOGRAPHY EASTMAN KODAK COMPANY (US) 1984-01-17 US claimed
CN-120005335-A Perfluororubber composition, preparation method thereof and product 上海芯密科技股份有限公司 2025-05-16 CN disclosed
CN-119264667-A High expansion rate silicone rubber cold shrink tube 任丘市恒威通信设备有限公司 2025-01-07 CN disclosed
CN-117285437-B Bexarotene derivative, preparation method and application thereof, and anti-tumor drug 沈阳药科大学 2024-09-17 CN disclosed
US-RE30495-E HERBICIDES STAUFFER CHEMICAL COMPANY (US) 1981-01-27 US disclosed
US-4246196-A CHEMICAL INTERMEDIATES IN THE PRODUCTION OF AMINOBENZIMIDAZOLONES HOECHST AG. (DE) 1981-01-20 US disclosed
US-3965087-A Trisazo dye containing a diphenylenesulfone structure SAKAI CHEMICAL INDUSTRY COMPANY LTD. (JA) 1976-06-22 US disclosed
US-3951941-A POLYAZODYE SAKAI CHEMICAL INDUSTRY COMPANY, LIMITED (JA) 1976-04-20 US disclosed