Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904721 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDHDAC1HDAC3HDAC2 | |
| Hydrochloric Acid SCHEMBL11503558 | 0.98 | HDAC1 (0.59) | ALDH1A1HPGDHDAC1HDAC3HDAC2 | |
| Aniline SCHEMBL22169226 | 0.92 | HDAC1 (0.58) | ALDH1A1HPGDHDAC1HDAC3HDAC2 | |
| SCHEMBL12075892 | 0.88 | HDAC1 (0.63) | ALDH1A1HPGDHDAC1HDAC3HDAC2 | |
| Trifluoroacetic Acid SCHEMBL3600531 | 0.88 | HDAC1 (0.54) | ALDH1A1HPGDHDAC1HDAC3HDAC2 | |
| SCHEMBL19448679 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HPGDHDAC1HDAC3HDAC2 | |
| SCHEMBL6689158 | 0.84 | ALDH1A1 (0.74) | ALDH1A1HPGDMAPK1POLBCYP2C19 | |
| SCHEMBL674397 | 0.83 | HDAC1 (0.59) | HDAC1HDAC3HDAC2MAPK1HDAC10 | |
| SCHEMBL5516360 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HPGDHDAC1HDAC3HDAC2 | |
| SCHEMBL3071688 | 0.82 | HDAC3 (0.64) | HDAC1HDAC3HDAC2MAPK1HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 620 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716344-B | 2- ((2-acetamidophenyl) amino) acetamido compound and preparation method and application thereof | 湖南科技大学 | 2023-12-22 | — | — | CN | claimed |
| CN-114308124-B | High-efficiency catalyst for nitrogen fixation and preparation method and application thereof | 杭州师范大学 | 2023-12-19 | — | — | CN | claimed |
| CN-114409657-B | 4-aryl (methyl) imidazoline quinoxalinone compound and preparation method and application thereof | 湖南科技大学 | 2023-02-24 | — | — | CN | claimed |
| CN-111217712-B | Method for preparing o-phenylenediamine from aniline | 江苏扬农化工集团有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-114716344-A | 2- ((2-acetamidophenyl) amino) acetyl arylamine compound and preparation method and application thereof | 湖南科技大学 | 2022-07-08 | — | — | CN | claimed |
| CN-114409657-A | 4-aryl (methyl) imidazoline quinoxalinone compound and preparation method and application thereof | 湖南科技大学 | 2022-04-29 | — | — | CN | claimed |
| CN-114308124-A | Efficient catalyst for nitrogen fixation and preparation method and application thereof | 杭州师范大学 | 2022-04-12 | — | — | CN | claimed |
| CN-107698484-A | A kind of preparation method of derivative of lenalidomide and application | 广东中科药物研究有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-107286043-A | The preparation method of 2- methoxyl group -5- acetylaminoanilines | 上海安诺其集团股份有限公司 | 2017-10-24 | — | — | CN | claimed |
| US-9745288-B2 | Compounds and methods for treating cancer by inhibiting the urokinase receptor | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-08-29 | — | — | US | claimed |
| EP-1692097-B1 | TRICYCLIC HYDROXAMATE AND BENZAMIDE DERIVATIVES, COMPOSITIONS AND METHODS | EXONHIT THERAPEUTICS SA (FR) | 2009-09-02 | — | — | EP | claimed |
| EP-1819341-A2 | IL-12 MODULATORY COMPOUNDS | Synta Pharmaceuticals Corporation (US) | 2007-08-22 | — | — | EP | claimed |
| US-20070129368-A1 | Tricyclic hydroxamate and benzamide derivatives, compositions and methods | EXONHIT THERAPEUTICS S.A. (FR) | 2007-06-07 | — | — | US | claimed |
| US-20060223996-A1 | IL-12 modulatory compounds | SYNTA PHARMACEUTICALS CORP. (US) | 2006-10-05 | — | — | US | claimed |
| WO-2006053227-A2 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2006-05-18 | — | — | WO | claimed |
| EP-1541549-A1 | Tricyclic hydroxamate and benzaminde derivatives, compositions and methods | Exonhit Therapeutics S.A. (FR) | 2005-06-15 | — | — | EP | claimed |
| US-20040224992-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-11-11 | — | — | US | claimed |
| WO-2004092142-A1 | AN IMPROVED PROCESS FOR MANUFACTURE OF SUBSTITUTED BENZIMIDAZOLES | IPCA LABORATORIES LIMITED (IN) | 2004-10-28 | — | — | WO | claimed |
| WO-2004075864-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-09-10 | — | — | WO | claimed |
| US-4711956-A | GRAMPOSITIVE, GRAMNEGATIVE BACTERIA | TPO "PHARMACHIM" (BG) | 1987-12-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223996-A1 | IL-12 modulatory compounds | IL2, IL4, IFNG | ALDH1A1 1381/4885HPGD 146/4885HDAC1 357/4885 |
| US-20070129368-A1 | Tricyclic hydroxamate and benzamide derivatives, compositions and methods | HDAC5, HDAC1, HDAC2 | ALDH1A1 1128/4885HPGD 334/4885HDAC1 2/4885 |
| US-20040224992-A1 | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | NR3C1, NR3C2, MC2R | ALDH1A1 2788/4885HPGD 1351/4885HDAC1 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.