Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 11/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947871 | 0.89 | DRD2 (0.54) | DRD2SIGMAR1CACNA1HMEN1KMT2A | |
| SCHEMBL25031746 | 0.88 | DRD2 (0.55) | DRD2SIGMAR1CACNA1HMEN1KMT2A | |
| SCHEMBL16480069 | 0.86 | CACNA1H (0.54) | DRD2CACNA1HTDP1 | |
| SCHEMBL31305414 | 0.84 | DRD2 (0.50) | DRD2SIGMAR1CACNA1HTDP1 | |
| SCHEMBL25755480 | 0.83 | DRD2 (0.40) | DRD2SIGMAR1CACNA1HTDP1 | |
| SCHEMBL13021104 | 0.81 | DRD2 (0.46) | DRD2SIGMAR1CACNA1HTDP1 | |
| SCHEMBL31615835 | 0.81 | SIGMAR1 (0.41) | DRD2SIGMAR1CACNA1H | |
| SCHEMBL31615644 | 0.80 | DRD2 (0.41) | DRD2SIGMAR1CACNA1H | |
| SCHEMBL21069638 | 0.79 | DRD2 (0.46) | DRD2SIGMAR1CACNA1HTDP1 | |
| SCHEMBL28927100 | 0.79 | MEN1 (0.49) | DRD2SIGMAR1CACNA1HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134104-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2023-02-15 | — | — | EP | disclosed |