Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947871 | 0.96 | DRD2 (0.54) | DRD2TDP1SIGMAR1MEN1KMT2A | |
| SCHEMBL16480069 | 0.90 | CACNA1H (0.54) | DRD2TDP1CACNA1HEPHX1 | |
| SCHEMBL25032149 | 0.88 | HRH3 (0.48) | DRD2TDP1SIGMAR1MEN1KMT2A | |
| SCHEMBL3524057 | 0.87 | DRD2 (0.66) | DRD2TDP1SIGMAR1MAOAMAOB | |
| SCHEMBL24619896 | 0.84 | DRD2 (0.54) | DRD2TDP1SIGMAR1MAOAMAOB | |
| SCHEMBL22699069 | 0.84 | DRD2 (0.54) | DRD2TDP1SIGMAR1MEN1KMT2A | |
| SCHEMBL4572542 | 0.84 | DRD2 (0.60) | DRD2TDP1SIGMAR1MAOAMAOB | |
| SCHEMBL31596990 | 0.84 | DRD2 (0.58) | DRD2TDP1SIGMAR1MAOAMAOB | |
| SCHEMBL8254760 | 0.84 | DRD2 (0.64) | DRD2TDP1SIGMAR1MEN1KMT2A | |
| SCHEMBL6700 | 0.83 | DRD2 (0.53) | DRD2TDP1SIGMAR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134104-A1 | TARGETED PROTEASE DEGRADATION (TED) PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2023-02-15 | — | — | EP | disclosed |