Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | STAT6 | P42226 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.31 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832674 | 1.00 | LMNA (0.31) | LMNAADRA2ACYP2D6CYP2C9DRD2 | |
| SCHEMBL20927651 | 0.85 | F2 (0.34) | F2KCNQ4KCNQ5GPR119 | |
| SCHEMBL29811656 | 0.84 | PDK1 (0.37) | LMNAGPR119 | |
| SCHEMBL23144580 | 0.84 | PDK1 (0.37) | LMNAGPR119 | |
| SCHEMBL29811519 | 0.83 | SMN1; SMN2 (0.40) | LMNAADRA2ACYP2D6CYP2C9DRD2 | |
| SCHEMBL23144640 | 0.83 | SMN1; SMN2 (0.40) | LMNAADRA2ACYP2D6CYP2C9DRD2 | |
| SCHEMBL25033220 | 0.83 | GPR119 (0.33) | LMNAGPR119 | |
| SCHEMBL31270355 | 0.83 | GPR119 (0.33) | LMNAGPR119 | |
| SCHEMBL23144395 | 0.83 | HRH4 (0.38) | LMNAKCNQ4KCNQ5GPR119 | |
| SCHEMBL29812119 | 0.83 | HRH4 (0.38) | LMNAKCNQ4KCNQ5GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |