Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | INSR | P06213 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184662 | 1.00 | PDE4B (0.36) | PDE4BPDE4DMAPTALDH1A1KDM4E | |
| SCHEMBL30832685 | 0.94 | PDE4B (0.39) | PDE4BPDE4DMAPTALDH1A1KDM4E | |
| SCHEMBL30871276 | 0.83 | INSR (0.41) | MAPTALDH1A1KDM4EPOLBGAA | |
| SCHEMBL25033063 | 0.83 | INSR (0.41) | MAPTALDH1A1KDM4EPOLBGAA | |
| SCHEMBL30184470 | 0.81 | LMNA (0.35) | PDE4BPDE4DMAPTALDH1A1KDM4E | |
| SCHEMBL25030907 | 0.81 | LMNA (0.35) | PDE4BPDE4DMAPTALDH1A1KDM4E | |
| SCHEMBL25033612 | 0.75 | INSR (0.32) | MAPTALDH1A1KMT2AINSRIGF1R | |
| SCHEMBL30184541 | 0.75 | INSR (0.35) | INSRIGF1RALK | |
| SCHEMBL26983715 | 0.74 | ALDH1A1 (0.47) | MAPTALDH1A1POLBGAAHTT | |
| SCHEMBL25032398 | 0.72 | LRRK2 (0.49) | MAPTALDH1A1KDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023016434-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-02-16 | — | — | WO | disclosed |