Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PLD2 | O14939 | 1/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13575598 | 0.84 | MEN1 (0.71) | MEN1KMT2APKMEZH2L3MBTL1 | |
| SCHEMBL10144490 | 0.84 | HTR4 (0.61) | MEN1KMT2APKMHTR4MAPK1 | |
| SCHEMBL10093241 | 0.83 | PKM (0.52) | MEN1KMT2APKMEZH2HTR4 | |
| SCHEMBL13880856 | 0.83 | MAPK1 (0.56) | MEN1KMT2APKMEZH2HTR4 | |
| SCHEMBL2546256 | 0.81 | MAPK14 (0.52) | MEN1KMT2AHTR4MAPK1OPRK1 | |
| SCHEMBL13880649 | 0.81 | MAPK1 (0.58) | MEN1KMT2AHTR4MAPK1OPRK1 | |
| SCHEMBL12825891 | 0.81 | PKM (0.50) | MEN1KMT2APKMEZH2HTR4 | |
| SCHEMBL30923249 | 0.80 | GRM5 (0.53) | MEN1KMT2AMAPK1L3MBTL1ATM | |
| SCHEMBL12825174 | 0.80 | KMT2A (0.57) | MEN1KMT2AMAPK1OPRK1L3MBTL1 | |
| SCHEMBL1927002 | 0.80 | KMT2A (0.54) | MEN1KMT2AHTR4MAPK1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018238-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023017446-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |