Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475479 | 1.00 | TDP1 (0.51) | TDP1ALDH1A1EGFRL3MBTL1SIRT5 | |
| SCHEMBL25033927 | 0.91 | TDP1 (0.48) | TDP1ALDH1A1L3MBTL1SIRT5S1PR1 | |
| SCHEMBL30475442 | 0.82 | L3MBTL1 (0.44) | ALDH1A1EGFRL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL25819474 | 0.80 | DHFR (0.48) | DHFR | |
| SCHEMBL1520429 | 0.80 | TDP1 (0.72) | TDP1ALDH1A1EGFRMAPTSMN1; SMN2 | |
| SCHEMBL25035196 | 0.78 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL25033924 | 0.76 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTSMN1; SMN2DHFR | |
| SCHEMBL30475472 | 0.75 | HPGD (0.43) | ALDH1A1L3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL25819476 | 0.74 | MAPT (0.44) | ALDH1A1L3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL11509277 | 0.73 | TDP1 (0.57) | TDP1ALDH1A1L3MBTL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017446-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023018238-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |