Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 15/20 | 0.32 |
| ▸ | JAK3 | P52333 | 10/20 | 0.32 |
| ▸ | JAK1 | P23458 | 9/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850992 | 0.80 | JAK3 (0.33) | JAK2JAK3JAK1TYK2 | |
| SCHEMBL22325300 | 0.80 | JAK3 (0.33) | JAK2JAK3JAK1TYK2 | |
| SCHEMBL29950366 | 0.80 | JAK3 (0.33) | JAK2JAK3JAK1TYK2 | |
| SCHEMBL25035690 | 0.74 | JAK3 (0.40) | JAK2JAK3JAK1TYK2 | |
| SCHEMBL25035696 | 0.74 | JAK2 (0.57) | JAK2JAK3JAK1TYK2 | |
| SCHEMBL31419838 | 0.74 | JAK2 (0.55) | JAK2JAK3JAK1TYK2 | |
| SCHEMBL13678272 | 0.72 | JAK2 (0.55) | JAK2JAK3JAK1TYK2 | |
| Phosphoric Acid SCHEMBL29378441 | 0.70 | JAK2 (0.59) | JAK2JAK3JAK1TYK2 | |
| SCHEMBL24258064 | 0.70 | ALDH1A1 (0.33) | JAK2JAK3JAK1TYK2 | |
| SCHEMBL22325267 | 0.70 | JAK2 (0.31) | JAK2JAK3JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018954-A1 | TREATMENT OF JAK-INHIBITION-RESPONSIVE DISORDERS WITH PRODRUGS OF JAK INHIBITORS | CONCERT PHARMACEUTICALS, INC. (US) | 2023-02-16 | — | — | WO | disclosed |