SCHEMBL25036

SCHEMBL25036

[c]1ccc2cccoc1-2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6829225 0.85 ALDH1A1 (0.40)
SCHEMBL290547 0.74 ALDH1A1 (0.43)
SCHEMBL5539585 0.73 NPC1 (0.39)
SCHEMBL512152 0.73 CYP1A2 (0.46)
SCHEMBL21295764 0.73 NOTUM (0.46)
SCHEMBL16401811 0.73 ALDH1A1 (0.46)
SCHEMBL3785401 0.73 TAAR1 (0.46)
SCHEMBL5539417 0.73 PTGS1 (0.38)
SCHEMBL21295725 0.69 ALDH1A1 (0.52)
SCHEMBL5534498 0.69 KIF11 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5036 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE49118-E1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-28 US claimed
CN-112390811-B Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-03-04 CN claimed
CN-114057711-A Anthracene ketone spiro derivative and preparation method and application thereof 中国科学院理化技术研究所 2022-02-18 CN claimed
CN-107556298-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-12-21 CN claimed
CN-107586290-B Aromatic heterocyclic derivative, material for organic electroluminescent element, and organic electroluminescent element 出光兴产株式会社 2021-05-11 CN claimed
EP-3201208-B1 BORONIC ACID DERIVATIVES MERCK PATENT GMBH (DE) 2021-03-24 EP claimed
EP-3201207-B1 BORONIC ACID DERIVATIVES MERCK PATENT GMBH (DE) 2021-02-24 EP claimed
CN-112390811-A Dithia-anthrone derivative and preparation method and application thereof 中国科学院理化技术研究所 2021-02-23 CN claimed
CN-107001391-B Boronic acid derivatives 默克专利股份公司 2020-11-27 CN claimed
US-10669289-B2 Boronic acid derivatives MERCK PATENT GMBH (DE) 2020-06-02 US claimed
EP-0479892-A1 FUSED-RING ARYL SUBSTITUTED IMIDAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-15 EP claimed
WO-1991015206-A1 TREATMENT OF GLAUCOMA AND OCULAR HYPERTENSION WITH IMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-17 WO claimed
WO-1991014367-A1 TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS WITH IMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-10-03 WO claimed
US-5034531-A Viricides SCHERING CORPORATION (US) 1991-07-23 US claimed
WO-1991000281-A2 FUSED-RING ARYL SUBSTITUTED IMIDAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-10 WO claimed
EP-0091213-B1 PESTICIDAL DRY-FORM SEED TREATER COMPOSITIONS FMC Corporation (US) 1988-09-28 EP claimed
US-4751222-A 2,3,4,5-tetrahydro-1H-3-benzazepines and CNS affecting use thereof NOVO INDUSTRI A/S (DK) 1988-06-14 US claimed
EP-0267740-A1 Naphthyridine and pyridopyrazine compounds and pharmaceutical usage thereof SCHERING CORPORATION (US) 1988-05-18 EP claimed
US-4650797-A HYPOTENSIVES E. R. SQUIBB & SONS, INC. (US) 1987-03-17 US claimed
EP-0204317-A2 2-Thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters E.R. Squibb &amp; Sons, Inc. (US) 1986-12-10 EP claimed