Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297554 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL25036 | 0.74 | — | — | |
| SCHEMBL6829225 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL208436 | 0.71 | — | — | |
| SCHEMBL1799678 | 0.71 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL162083 | 0.70 | TAAR1 (0.62) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL11073018 | 0.69 | TAAR1 (0.60) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| Hydrochloric Acid SCHEMBL8104290 | 0.69 | TAAR1 (0.60) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL244155 | 0.67 | — | — | |
| SCHEMBL7404185 | 0.67 | TAAR1 (0.64) | ALDH1A1KDM4EHSD17B10HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637533-B1 | Substituted thiazolopyrimidines as analgesics | GRUENENTHAL GMBH (DE) | 2008-08-13 | — | — | EP | claimed |
| US-20050049292-A1 | Pyrrole-type compounds, compositions, and methods for treating cancer, treating viral diseases and causing immunosuppression | GEMIN X PHARMACEUTICALS CANADA INC. (CA) | 2005-03-03 | — | — | US | claimed |
| EP-2427186-A2 | DIHYDROOROTATE-DEHYDROGENASEE INHIBITORS AS VIROSTATIC COMPOUNDS | 4SC AG (DE) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128050-A2 | ANTI-INFLAMMATORY AGENTS AS VIROSTATIC COMPOUNDS | 4SC AG (DE) | 2010-11-11 | — | — | WO | disclosed |
| EP-1433781-B1 | Pyrrolidine carboxylic acid derivatives | MGI GP INC (US) | 2010-02-24 | — | — | EP | disclosed |
| EP-2004654-A2 | KINASE ANTAGONISTS | The Regents of the University of California (US) | 2008-12-24 | — | — | EP | disclosed |
| US-20080214600-A1 | Quaternized Quinuclidine Esters | ALMIRALL PRODESFARMA, SA (ES) | 2008-09-04 | — | — | US | disclosed |
| EP-1725552-B1 | NEW QUATERNIZED QUINUCLIDINE ESTERS | ALMIRALL LAB (ES) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007114926-A2 | KINASE ANTAGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-11 | — | — | WO | disclosed |
| US-7144912-B2 | Pyrrole-type compounds, compositions, and methods for treating cancer, treating viral diseases and causing immunosuppression | GEMIN X BIOTECHNOLOGIES INC. (CA) | 2006-12-05 | — | — | US | disclosed |
| EP-1725552-A1 | NEW QUATERNIZED QUINUCLIDINE ESTERS | Almirall Prodesfarma, S.A. (ES) | 2006-11-29 | — | — | EP | disclosed |
| EP-1427722-A2 | PYRROLE-TYPE COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING CANCER, TREATING VIRAL DISEASES AND CAUSING IMMUNOSUPPRESSION | Gemin X Biotechnologies Inc. (CA) | 2004-06-16 | — | — | EP | disclosed |
| US-6514998-B1 | For controlling animal pests and harmful fungi | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-04 | — | — | US | disclosed |
| WO-2003008410-A2 | POLYPYRROLES AS AGENTS FOR TREATING CANCER, TREATING VIRAL DISEASES AND CAUSING IMMUNOSUPPRESSION | GEMIN X BIOTECHNOLOGIES INC. (CA) | 2003-01-30 | — | — | WO | disclosed |
| EP-1259490-A2 | SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO AND ANALOGUES THEREOF | Sloan Kettering Institute For Cancer Research (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001064650-A2 | SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO AND ANALOGUES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH CENTER (US) | 2001-09-07 | — | — | WO | disclosed |
| US-5321000-A | Benzhydryl compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1994-06-14 | — | — | US | disclosed |
| US-5162537-A | To safen acetamide herbicids used to control grassy and broadleaf weeds in rice, sorghum and wheat | MONSANTO COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| US-4964893-A | REDUCING INJURY TO A CROP PLANT | MONSANTO COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| WO-1990008145-A1 | ANTI-INFLAMMATORY 1-HETEROARYL-3-ACYL-2-OXINDOLES | PFIZER INC. (US) | 1990-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214600-A1 | Quaternized Quinuclidine Esters | NQO2, QPCT, QARS1 | ALDH1A1 443/4885KDM4E 993/4885HSD17B10 1677/4885 |
| US-20050049292-A1 | Pyrrole-type compounds, compositions, and methods for treating cancer, treating viral diseases and causing immunosuppression | PYCR1, ZC3HAV1, POLI | ALDH1A1 3328/4885KDM4E 259/4885HSD17B10 3887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.