Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trepibutone SCHEMBL29441541 | 1.00 | TSHR (0.61) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| SCHEMBL11683269 | 0.92 | TSHR (0.51) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| SCHEMBL11684059 | 0.87 | HMGCR (0.51) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| SCHEMBL4264883 | 0.87 | KMT2A (0.53) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| SCHEMBL24651214 | 0.86 | TSHR (0.65) | TSHRCYP3A4HSD17B10CYP2C19KDM4E | |
| SCHEMBL24651215 | 0.83 | TSHR (0.43) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| Trepibutone SCHEMBL13725387 | 0.79 | ALDH1A1 (0.45) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| SCHEMBL31113388 | 0.79 | HTT (0.53) | CYP3A4HSD17B10HTTCYP2C19MEN1 | |
| SCHEMBL11684821 | 0.79 | TSHR (0.65) | TSHRCYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL24651298 | 0.79 | TSHR (0.51) | TSHRCYP3A4HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 919 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111413431-B | Method for screening metabolic markers of drug-induced acute kidney injury lesion process | 中国药科大学 | 2022-03-01 | — | — | CN | claimed |
| US-11136342-B2 | Carbonate prodrugs and methods of using the same | ACORDA THERAPEUTICS, INC. (US) | 2021-10-05 | — | — | US | claimed |
| US-11065205-B2 | Immediate/delayed drug delivery | DRUG DELIVERY INTERNATIONAL LIMITED (GB) | 2021-07-20 | — | — | US | claimed |
| WO-2020218950-A1 | COMBINATION FOR TREATING FUNCTIONAL DISEASES OF THE GASTROINTESTINAL TRACT | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "ВАЛЕНТА-ИНТЕЛЛЕКТ" | 2020-10-29 | — | — | WO | claimed |
| CN-111426766-A | Construction and evaluation method of drug-induced acute kidney injury mouse model | 中国药科大学 | 2020-07-17 | — | — | CN | claimed |
| CN-111413431-A | Method for screening metabolic markers of drug-induced acute kidney injury lesion process | 中国药科大学 | 2020-07-14 | — | — | CN | claimed |
| US-20200157126-A1 | CARBONATE PRODRUGS AND METHODS OF USING THE SAME | ACORDA THERAPEUTICS, INC. | 2020-05-21 | — | — | US | claimed |
| US-20190125679-A1 | IMMEDIATE/DELAYED DRUG DELIVERY | UNIVERSITY OF STRATHCLYDE (GB) | 2019-05-02 | — | — | US | claimed |
| EP-3373943-A1 | CONTROL OF CELLULAR REDOX LEVELS | Mckenna, Elizabeth (US) | 2018-09-19 | — | — | EP | claimed |
| CN-108430482-A | Control of cellular redox levels | 伊丽莎白·麦克纳 | 2018-08-21 | — | — | CN | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| WO-2006102029-A9 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE | DOV PHARMACEUTICAL INC (US) | 2006-12-07 | — | — | WO | claimed |
| WO-2006102029-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF URINARY INCONTINENCE | DOV PHARMACEUTICAL, INC. (US) | 2006-09-28 | — | — | WO | claimed |
| CN-1628698-A | Medicine for treating cholecystitis and biliary tract disease and its preparation method | YU FENG (CN) | 2005-06-22 | — | — | CN | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| US-5811547-A | Method for inducing crystalline state transition in medicinal substance | NIPPON SHINYAJU CO., LTD. (JP) | 1998-09-22 | — | — | US | claimed |
| WO-1998022114-A1 | A METHOD FOR PROMOTING TISSUE REPAIR | DUMEX-ALPHARMA A/S (DK) | 1998-05-28 | — | — | WO | claimed |
| US-3943169-A | DIURETIC, SPASMOLYTIC | TAKEDA CHEMICAL INDUSTRIES, LTD (JA) | 1976-03-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157126-A1 | CARBONATE PRODRUGS AND METHODS OF USING THE SAME | CA6, CA7, CA4 | TSHR 3093/4885CYP3A4 135/4885HSD17B10 702/4885 |
| US-11136342-B2 | Carbonate prodrugs and methods of using the same | CA6, CA7, CA4 | TSHR 3093/4885CYP3A4 135/4885HSD17B10 702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.