Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trepibutone SCHEMBL25039 | 1.00 | TSHR (0.61) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| SCHEMBL11683269 | 0.92 | TSHR (0.51) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| SCHEMBL11684059 | 0.87 | HMGCR (0.51) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| SCHEMBL4264883 | 0.87 | KMT2A (0.53) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| SCHEMBL24651214 | 0.86 | TSHR (0.65) | TSHRCYP3A4HSD17B10CYP2C19KDM4E | |
| SCHEMBL24651215 | 0.83 | TSHR (0.43) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| Trepibutone SCHEMBL13725387 | 0.79 | ALDH1A1 (0.45) | TSHRCYP3A4HSD17B10HTTCYP2C19 | |
| SCHEMBL31113388 | 0.79 | HTT (0.53) | CYP3A4HSD17B10HTTCYP2C19MEN1 | |
| SCHEMBL11684821 | 0.79 | TSHR (0.65) | TSHRCYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL24651298 | 0.79 | TSHR (0.51) | TSHRCYP3A4HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230407360-A1 | Recombinant Production of Steviol Glycosides | EVOLVA SA (CH) | 2023-12-21 | — | — | US | claimed |
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-18 | — | — | US | claimed |
| EP-4043478-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITING ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-08-17 | — | — | EP | claimed |
| US-20220228185-A1 | Recombinant Production of Steviol Glycosides | EVOLVA SA (CH) | 2022-07-21 | — | — | US | claimed |
| US-20260144799-A1 | COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER | Revolution Medicines, Inc. (US) | 2026-05-28 | — | — | US | disclosed |
| EP-4027995-B1 | HPK1 ANTAGONISTS AND USES THEREOF | NIMBUS SATURN INC (US) | 2026-05-27 | — | — | EP | disclosed |
| US-20260092097-A1 | MULTIMERIC IL-15 SOLUBLE FUSION MOLECULES AND METHODS OF MAKING AND USING SAME | ALTOR BIOSCIENCE LLC (US) | 2026-04-02 | — | — | US | disclosed |
| US-20260092310-A1 | CAS12A COMPOSITIONS AND METHODS | NEW ENGLAND BIOLABS, INC. (US) | 2026-04-02 | — | — | US | disclosed |
| US-12545903-B2 | Polypeptide assemblies and methods for the production thereof | UNIVERSITY OF WASHINGTON (US) | 2026-02-10 | — | — | US | disclosed |
| US-12497376-B2 | Compound [2-(dimethylamino)-2-phenylbutyl]-3,4,5-trimethoxybenzoate 4-methyl-2H-chromen-2-on-7-yl sulphate and use thereof | LTD “VALENTA—INTELLEKT” (RU) | 2025-12-16 | — | — | US | disclosed |
| US-20250304941-A1 | Polypeptide Assemblies and Methods for the Production Thereof | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2025-10-02 | — | — | US | disclosed |
| US-20250283154-A1 | PROFILING OF BIOLOGICAL ANALYTES WITH SPATIALLY BARCODED OLIGONUCLEOTIDE ARRAYS | 10X GENOMICS, INC. | 2025-09-11 | — | — | US | disclosed |
| CN-113661248-B | Inhibition of unintended mutations in gene editing | 上海科技大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-114957433-A | Tropical rana grahami Fosl1 protein mutant and application thereof | 暨南大学 | 2022-08-30 | — | — | CN | disclosed |
| EP-4043478-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITING ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-08-17 | — | — | EP | disclosed |
| EP-4027995-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2022-07-20 | — | — | EP | disclosed |
| US-11384353-B2 | Inhibition of unintended mutations in gene editing | SHANGHAITECH UNIVERSITY (CN) | 2022-07-12 | — | — | US | disclosed |
| WO-2022071428-A1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION INCLUDING SAME | 住友化学株式会社 | 2022-04-07 | — | — | WO | disclosed |
| US-20220098594-A1 | COMPOSITIONS COMPRISING SASP MODULATORS AND SENESCENCE ATTENUATORS AND USES THEREOF FOR MODULATING CELLULAR SENESCENCE | RSEM, LIMITED PARTNERSHIP (CA) | 2022-03-31 | — | — | US | disclosed |
| CN-114174531-A | Profiling of biological analytes with spatially barcoded oligonucleotide arrays | 10X基因组学有限公司 | 2022-03-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12497376-B2 | Compound [2-(dimethylamino)-2-phenylbutyl]-3,4,5-trimethoxybenzoate 4-methyl-2H-chromen-2-on-7-yl sulphate and use thereof | UGT2B7, CYP3A7, SLC10A2 | TSHR 2668/4885CYP3A4 10/4885HSD17B10 482/4885 |
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | KRAS, NRAS, HRAS | TSHR 3295/4885CYP3A4 4653/4885HSD17B10 4794/4885 |
| US-20260092310-A1 | CAS12A COMPOSITIONS AND METHODS | RNASEL, RBM12, NT5C2 | TSHR 2177/4885CYP3A4 3209/4885HSD17B10 4509/4885 |
| US-20260092097-A1 | MULTIMERIC IL-15 SOLUBLE FUSION MOLECULES AND METHODS OF MAKING AND USING SAME | IL15, IL15RA, IL23R | TSHR 695/4885CYP3A4 2057/4885HSD17B10 2612/4885 |
| US-20260144799-A1 | COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER | PDCD1, CD274, PTPN1 | TSHR 1675/4885CYP3A4 4804/4885HSD17B10 3715/4885 |
| US-12545903-B2 | Polypeptide assemblies and methods for the production thereof | PICALM, PHAX, NSF | TSHR 4154/4885CYP3A4 4818/4885HSD17B10 3002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.