Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 6/20 | 0.37 |
| ▸ | METAP1 | P53582 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2504506 | 0.98 | SMN1; SMN2 (0.41) | SMN1; SMN2GAAMGAMSIMGAM2 | |
| SCHEMBL11194460 | 0.94 | TSHR (0.46) | TSHRKMT2AEPHX1ZDHHC7LMNA | |
| SCHEMBL17010280 | 0.94 | TSHR (0.46) | TSHRKMT2AEPHX1ZDHHC7LMNA | |
| SCHEMBL28677862 | 0.94 | TSHR (0.46) | TSHRKMT2AEPHX1ZDHHC7LMNA | |
| SCHEMBL28364726 | 0.94 | TSHR (0.46) | TSHRKMT2AEPHX1ZDHHC7LMNA | |
| SCHEMBL5123880 | 0.94 | TSHR (0.46) | TSHRKMT2AEPHX1ZDHHC7LMNA | |
| SCHEMBL11184643 | 0.92 | TSHR (0.43) | SMN1; SMN2TSHRMETAP2METAP1EPHX1 | |
| SCHEMBL8158861 | 0.91 | CPB2 (0.49) | SMN1; SMN2METAP2METAP1CPB2 | |
| SCHEMBL28250638 | 0.90 | ACHE (0.42) | SMN1; SMN2GAAMGAMSIMGAM2 | |
| SCHEMBL5011365 | 0.90 | ACHE (0.42) | SMN1; SMN2GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376133-B1 | MEDICAL ADHESIVE FOR SURGERY | BAYER MATERIALSCIENCE AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-2376133-B1 | MEDICAL ADHESIVE FOR SURGERY | BAYER MATERIALSCIENCE AG (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-2376133-A2 | MEDICAL ADHESIVE FOR SURGERY | Bayer MaterialScience AG (DE) | 2011-10-19 | — | — | EP | disclosed |
| US-20110245351-A1 | MEDICAL ADHESIVE FOR SURGERY | BAYER MATERIALSCIENCE AG (DE) | 2011-10-06 | — | — | US | disclosed |
| US-20110245351-A1 | MEDICAL ADHESIVE FOR SURGERY | BAYER MATERIALSCIENCE AG (DE) | 2011-10-06 | — | — | US | disclosed |
| WO-2010066356-A2 | MEDICAL ADHESIVE FOR SURGERY | BAYER MATERIALSCIENCE AG (DE) | 2010-06-17 | — | — | WO | disclosed |
| WO-2010066356-A2 | MEDICAL ADHESIVE FOR SURGERY | BAYER MATERIALSCIENCE AG (DE) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245351-A1 | MEDICAL ADHESIVE FOR SURGERY | ICAM1, EPCAM, PTK2 | SMN1; SMN2 4543/4885GAA 3977/4885MGAM 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.