Sugi Predict

Sugi Predict / Compounds / SCHEMBL5011365

SCHEMBL5011365

SCHEMBL5011365

CCCCNC(C)C(=O)OCC

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ACHE P22303 8/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ ZDHHC7 Q9NXF8 1/20 0.39
▸ MGAM O43451 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ SI P14410 1/20 0.38
▸ MGAM2 Q2M2H8 1/20 0.38
▸ METAP2 P50579 1/20 0.38
▸ METAP1 P53582 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ POLB P06746 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ FAAH O00519 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28250638 1.00 ACHE (0.42) ACHESMN1; SMN2ZDHHC7MGAMGAA
SCHEMBL11184643 0.94 TSHR (0.43) ACHESMN1; SMN2ZDHHC7METAP2METAP1
SCHEMBL28364726 0.92 TSHR (0.46) ZDHHC7TSHRKMT2AMEN1FAAH
SCHEMBL5123880 0.92 TSHR (0.46) ZDHHC7TSHRKMT2AMEN1FAAH
SCHEMBL11194460 0.92 TSHR (0.46) ZDHHC7TSHRKMT2AMEN1FAAH
SCHEMBL28677862 0.92 TSHR (0.46) ZDHHC7TSHRKMT2AMEN1FAAH
SCHEMBL17010280 0.92 TSHR (0.46) ZDHHC7TSHRKMT2AMEN1FAAH
SCHEMBL2504506 0.92 SMN1; SMN2 (0.41) SMN1; SMN2MGAMGAASIMGAM2
SCHEMBL2504071 0.90 SMN1; SMN2 (0.41) SMN1; SMN2ZDHHC7MGAMGAASI
SCHEMBL11183460 0.88 SCN1A (0.44) MGAMGAASIMGAM2METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12121604-B2 Composition comprising hydroxylated diphenylmethane derivatives L'OREAL (FR) 2024-10-22 — — US claimed
CN-117338637-A Compositions comprising hydroxylated diphenylmethane derivatives 莱雅公司 2024-01-05 — — CN claimed
EP-3386469-A1 COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES L'OREAL (FR) 2018-10-17 — — EP claimed
US-20180263875-A1 COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES L'OREAL (FR) 2018-09-20 — — US claimed
WO-2017096583-A1 COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES L'OREAL (FR) 2017-06-15 — — WO claimed
US-12121604-B2 Composition comprising hydroxylated diphenylmethane derivatives L'OREAL (FR) 2024-10-22 — — US disclosed
CN-117338637-A Compositions comprising hydroxylated diphenylmethane derivatives 莱雅公司 2024-01-05 — — CN disclosed
EP-3386469-A1 COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES L'OREAL (FR) 2018-10-17 — — EP disclosed
CN-108601713-A The composition of oil-in-water emulsion form 莱雅公司 2018-09-28 — — CN disclosed
US-20180263875-A1 COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES L'OREAL (FR) 2018-09-20 — — US disclosed
US-20180014533-A1 INSECTICIDE COMPOSITION Zobele España, S.A. (ES) 2018-01-18 — — US disclosed
EP-3235382-A1 INSECTICIDE COMPOSITION Zobele España, S.A. (ES) 2017-10-25 — — EP disclosed
WO-2017096583-A1 COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES L'OREAL (FR) 2017-06-15 — — WO disclosed
US-20080131381-A1 METHODS FOR PHOTOSTABILIZING INGREDIENTS WITHIN COSMETICS, PERSONAL CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS OBTAINED THEREFROM MERCK PATENT GESELLSCHAFT (DE) 2008-06-05 — — US disclosed
US-7150876-B2 Methods for stabilizing ingredients within cosmetics, personal care and household products MERCK PATENT GMBH (DE) 2006-12-19 — — US disclosed
US-20050244349-A1 Methods for stabilizing ingredients within cosmetics, personal care and household products SUSONITY Commercial GmbH (DE) 2005-11-03 — — US disclosed
EP-1591099-A2 Methods for stabilizing ingredients within cosmetics, personal care and household products MERCK PATENT GmbH (DE) 2005-11-02 — — EP disclosed
US-4421693-A INSECTICIDES, MITICIDES OR NEMATOCIDES OTSUKA CHEMICAL CO., LTD. (JP) 1983-12-20 — — US disclosed
US-4413005-A 2,3-DIHYDRO-2,2-DIMETHYLBENZOFURAN-7-YL DERIVATIVES OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1983-11-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050244349-A1 Methods for stabilizing ingredients within cosmetics, personal care and household products CUTA, TYR, LAGE3 ACHE 1309/4885SMN1; SMN2 1823/4885ZDHHC7 403/4885
US-20080131381-A1 METHODS FOR PHOTOSTABILIZING INGREDIENTS WITHIN COSMETICS, PERSONAL CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS OBTAINED THEREFROM TYR, NISCH, PPOX ACHE 1311/4885SMN1; SMN2 3270/4885ZDHHC7 244/4885
US-20180263875-A1 COMPOSITION COMPRISING HYDROXYLATED DIPHENYLMETHANE DERIVATIVES DEGS1, ALOX5, ALOX12 ACHE 4313/4885SMN1; SMN2 2740/4885ZDHHC7 343/4885
US-12121604-B2 Composition comprising hydroxylated diphenylmethane derivatives DEGS1, ALOX5, ALOX12 ACHE 4313/4885SMN1; SMN2 2740/4885ZDHHC7 343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.