Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.46 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.46 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.46 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122436 | 0.89 | MGLL (0.57) | SRD5A2MGLLTEAD1TEAD4TEAD2 | |
| SCHEMBL25998844 | 0.86 | MRGPRX4 (0.57) | SRD5A2RXRARXRBRXRGKCNH2 | |
| SCHEMBL30201463 | 0.85 | SCN9A (0.60) | MGLLSCN9AF2F10PRSS1 | |
| SCHEMBL30201454 | 0.83 | FGFR1 (0.55) | SCN9AF2F10PRSS1FGFR1 | |
| SCHEMBL24950460 | 0.83 | FGFR1 (0.55) | SCN9AF2F10PRSS1FGFR1 | |
| SCHEMBL31312713 | 0.83 | F2 (0.42) | SRD5A2MGLLSCN9ACES2CES1 | |
| SCHEMBL30201485 | 0.82 | SCN9A (0.48) | SCN9ACDC7CDK2F2F10 | |
| SCHEMBL25041611 | 0.80 | TEAD1 (0.51) | SRD5A2MGLLTEAD1TEAD4TEAD2 | |
| SCHEMBL2610308 | 0.76 | MGLL (0.53) | MGLLTEAD1TEAD4TEAD2TEAD3 | |
| SCHEMBL29892816 | 0.76 | KCNH2 (0.58) | SRD5A2MGLLTEAD1TEAD4TEAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |