Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20744890 | 0.78 | HPGD (0.42) | CYP2C19HIF1ASMN1; SMN2ALOX15HPGD | |
| SCHEMBL20744888 | 0.78 | HPGD (0.42) | CYP2C19HIF1ASMN1; SMN2ALOX15HPGD | |
| SCHEMBL25890199 | 0.75 | MAPT (0.44) | MAPTKMT2ACYP2C19HIF1AALOX15 | |
| SCHEMBL20745215 | 0.75 | GPR55 (0.36) | CYP2C19HIF1ASMN1; SMN2GPR55 | |
| SCHEMBL20745216 | 0.75 | GPR55 (0.36) | CYP2C19HIF1ASMN1; SMN2GPR55 | |
| SCHEMBL20744889 | 0.75 | HPGD (0.39) | MAPTKMT2ACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL20744891 | 0.75 | HPGD (0.39) | MAPTKMT2ACYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL20744868 | 0.72 | HPGD (0.41) | CYP2C19HIF1ASMN1; SMN2ALOX15HPGD | |
| SCHEMBL20744865 | 0.72 | HPGD (0.41) | CYP2C19HIF1ASMN1; SMN2ALOX15HPGD | |
| SCHEMBL28399342 | 0.71 | TRPA1 (0.38) | HPGDL3MBTL1GLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230046065-A1 | MERGING C(sp3)-H ACTIVATION WITH DNA-ENCODING | THE SCRIPPS RESEARCH INSTITUTE | 2023-02-16 | — | — | US | disclosed |