Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18974769 | 0.78 | USP30 (0.42) | ALDH1A1KDM4EGAAIDO1MAPT | |
| SCHEMBL18974772 | 0.78 | L3MBTL1 (0.51) | ALDH1A1KDM4EGAAIDO1MAPT | |
| SCHEMBL13992667 | 0.78 | PDK1 (0.51) | ALDH1A1KDM4EGAAIDO1MAPT | |
| SCHEMBL6113932 | 0.78 | AR (0.42) | KMT2A | |
| SCHEMBL28344665 | 0.76 | L3MBTL1 (0.42) | ALDH1A1KDM4EGAAMAPTL3MBTL1 | |
| SCHEMBL20888953 | 0.76 | KDM4E (0.47) | ALDH1A1KDM4EGAAIDO1MAPT | |
| SCHEMBL6114102 | 0.74 | ALDH1A1 (0.41) | ALDH1A1IDO1MAPTHDAC1KMT2A | |
| SCHEMBL21992444 | 0.74 | KDM4E (0.46) | ALDH1A1KDM4EGAAIDO1MAPT | |
| SCHEMBL2248326 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL11164984 | 0.73 | MAPT (0.46) | ALDH1A1KDM4EGAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018636-A1 | COMPOUNDS THAT INHIBIT PI3K ISOFORM ALPHA AND METHODS FOR TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2023-02-16 | — | — | WO | disclosed |