Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 13/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 12/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25949203 | 0.85 | PI4KA (0.47) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18571696 | 0.85 | PI4KA (0.47) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL18571700 | 0.85 | PI4KA (0.47) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL25047763 | 0.84 | PI4KA (0.40) | ADKPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL25047420 | 0.83 | PRMT5 (0.34) | PRMT5WDR77DOT1L | |
| SCHEMBL29743109 | 0.83 | PRMT5 (0.34) | PRMT5WDR77DOT1L | |
| SCHEMBL25047839 | 0.80 | DOT1L (0.34) | PI4KAPI4K2BPI4K2API4KBPRMT5 | |
| SCHEMBL22002162 | 0.79 | PRMT5 (0.37) | PRMT5WDR77RXFP1 | |
| SCHEMBL22002064 | 0.78 | PRMT5 (0.35) | PI4KAPI4K2BPI4K2API4KBPRMT5 | |
| SCHEMBL20721509 | 0.78 | PRMT5 (0.46) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |