Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 7/20 | 0.34 |
| ▸ | AMD1 | P17707 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 6/20 | 0.32 |
| ▸ | PRMT9 | Q6P2P2 | 1/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046560 | 0.84 | ADK (0.41) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL25047819 | 0.80 | WDR5 (0.33) | ADKPRMT5PRMT9METTL3 | |
| SCHEMBL25047770 | 0.78 | SRC (0.33) | ADK | |
| SCHEMBL25047424 | 0.75 | ADK (0.45) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL18571623 | 0.71 | PI4KA (0.62) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL20239108 | 0.71 | ADK (0.46) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL18571700 | 0.71 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL4896950 | 0.71 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL12379190 | 0.71 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL18512601 | 0.71 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |