Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.32 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048261 | 0.84 | IGF1R (0.36) | PRMT5METTL3IGF1R | |
| SCHEMBL25048329 | 0.78 | PRMT5 (0.40) | PRMT5METTL3IGF1R | |
| SCHEMBL25048728 | 0.77 | PRMT5 (0.39) | PRMT5METTL3 | |
| SCHEMBL25046601 | 0.74 | PRMT5 (0.46) | PRMT5METTL3 | |
| SCHEMBL25048325 | 0.74 | PRMT5 (0.37) | PRMT5METTL3IGF1R | |
| SCHEMBL25046638 | 0.73 | PRMT5 (0.38) | PRMT5METTL3IGF1R | |
| SCHEMBL25049348 | 0.73 | IGF1R (0.37) | PRMT5METTL3IGF1R | |
| SCHEMBL25047713 | 0.73 | PRMT5 (0.41) | PRMT5METTL3 | |
| SCHEMBL25048258 | 0.73 | PRMT5 (0.49) | PRMT5METTL3 | |
| SCHEMBL31618087 | 0.73 | PRMT5 (0.49) | PRMT5METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |