Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ABL2 | P42684 | 1/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048329 | 0.92 | PRMT5 (0.40) | IGF1RPRMT5WDR77ABL1EGFR | |
| SCHEMBL25048728 | 0.91 | PRMT5 (0.39) | PRMT5WDR77PIP4K2AMETTL3 | |
| SCHEMBL25046638 | 0.88 | PRMT5 (0.38) | IGF1RPRMT5WDR77PIP4K2AMETTL3 | |
| SCHEMBL25047713 | 0.88 | PRMT5 (0.41) | PRMT5WDR77PIP4K2AMETTL3 | |
| SCHEMBL25048325 | 0.87 | PRMT5 (0.37) | IGF1RPRMT5WDR77PIP4K2AMETTL3 | |
| SCHEMBL25048258 | 0.86 | PRMT5 (0.49) | PRMT5WDR77METTL3 | |
| SCHEMBL31618087 | 0.86 | PRMT5 (0.49) | PRMT5WDR77METTL3 | |
| SCHEMBL25046625 | 0.84 | PRMT5 (0.32) | IGF1RPRMT5METTL3 | |
| SCHEMBL25049348 | 0.83 | IGF1R (0.37) | IGF1RPRMT5WDR77METTL3LCK | |
| SCHEMBL25046633 | 0.82 | PIP4K2A (0.38) | PRMT5WDR77PIP4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |