SCHEMBL25046664

SCHEMBL25046664

C=C/C(=C\C)CCN(CCCN(C[C@H]1C[C@@H](n2cc(C3CC3)c3c(N)ncnc32)[C@@H]2OC(C)(C)O[C@H]12)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ METTL3 Q86U44 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25048862 0.91 MTOR (0.34) —
SCHEMBL25047981 0.90 RET (0.32) —
SCHEMBL25047933 0.88 METTL3 (0.37) METTL3
SCHEMBL25048851 0.81 SRC (0.32) —
SCHEMBL25048523 0.81 ADK (0.39) —
SCHEMBL25047532 0.80 PRMT5 (0.42) METTL3
SCHEMBL25046676 0.80 SRC (0.34) METTL3
SCHEMBL25048500 0.79 SRC (0.33) —
SCHEMBL25047942 0.78 ADK (0.33) —
SCHEMBL25048829 0.77 METTL3 (0.37) METTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023017152-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2023-02-16 — — WO disclosed
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