Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048095 | 0.90 | PARP1 (0.32) | TRPV6 | |
| SCHEMBL25048458 | 0.85 | CHKA (0.34) | CHKANT5EPRMT5 | |
| SCHEMBL25048345 | 0.82 | CHKA (0.35) | CHKANT5E | |
| SCHEMBL25048059 | 0.81 | CHKA (0.32) | CHKANT5E | |
| SCHEMBL25046781 | 0.79 | CHKA (0.38) | CHKA | |
| SCHEMBL25046819 | 0.78 | PRMT5 (0.40) | NT5EPRMT5 | |
| SCHEMBL30941211 | 0.78 | PRMT5 (0.40) | NT5EPRMT5 | |
| SCHEMBL25047669 | 0.77 | CHKA (0.33) | CHKA | |
| SCHEMBL25048731 | 0.76 | PIK3CA (0.36) | CHKATRPV6 | |
| SCHEMBL25049274 | 0.75 | CHKA (0.35) | CHKANT5EPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |