Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 3/20 | 0.35 |
| ▸ | NT5E | P21589 | 2/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.32 |
| ▸ | PDE8A | O60658 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048385 | 0.88 | ROCK2 (0.39) | CHKANT5EPDE8AHRH3 | |
| SCHEMBL25049275 | 0.84 | PRMT5 (0.45) | PRMT5WDR77 | |
| SCHEMBL25047863 | 0.82 | METTL3 (0.34) | CHKATPSAB1PDE8A | |
| SCHEMBL25048806 | 0.81 | CHKA (0.35) | CHKANT5ECHKB | |
| SCHEMBL31617909 | 0.81 | CHKA (0.35) | CHKANT5ECHKB | |
| SCHEMBL25049069 | 0.81 | CHKA (0.33) | CHKACHKB | |
| SCHEMBL25046778 | 0.81 | CHKA (0.37) | CHKANT5ECHKBOPRM1OPRD1 | |
| SCHEMBL25048345 | 0.79 | CHKA (0.35) | CHKANT5ECHKB | |
| SCHEMBL25048835 | 0.78 | PRMT5 (0.41) | NT5EPRMT5WDR77 | |
| SCHEMBL25048458 | 0.78 | CHKA (0.34) | CHKANT5EPRMT5CHKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |