Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | ABL2 | P42684 | 2/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.38 |
| ▸ | IGF1R | P08069 | 2/20 | 0.36 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048771 | 0.91 | RIPK2 (0.41) | METTL3EGFRABL1ABL2ADCY5 | |
| SCHEMBL25047460 | 0.85 | METTL3 (0.48) | METTL3DOT1L | |
| SCHEMBL31618109 | 0.85 | METTL3 (0.48) | METTL3DOT1L | |
| SCHEMBL25048776 | 0.83 | EGFR (0.40) | METTL3EGFRABL1ABL2ADCY5 | |
| SCHEMBL25048517 | 0.80 | ABL1 (0.40) | METTL3EGFRABL1ABL2ADCY5 | |
| SCHEMBL25047518 | 0.77 | ABL1 (0.44) | METTL3EGFRABL1ABL2ADCY5 | |
| SCHEMBL25047965 | 0.76 | ABL1 (0.54) | EGFRABL1ABL2IGF1RRET | |
| SCHEMBL25048766 | 0.76 | METTL3 (0.50) | METTL3 | |
| SCHEMBL31618069 | 0.76 | METTL3 (0.50) | METTL3 | |
| SCHEMBL25048005 | 0.76 | ABL1 (0.43) | EGFRABL1ABL2ADCY5IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |