Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABL2 | P42684 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 2/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 6/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | SIK1 | P57059 | 1/20 | 0.37 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | DSTYK | Q6XUX3 | 1/20 | 0.37 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.36 |
| ▸ | NEK7 | Q8TDX7 | 3/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048771 | 0.90 | RIPK2 (0.41) | EGFRABL1ABL2IGF1RRIPK2 | |
| SCHEMBL25046820 | 0.85 | CA2 (0.47) | PRMT5METTL3 | |
| SCHEMBL31618068 | 0.85 | CA2 (0.47) | PRMT5METTL3 | |
| SCHEMBL25047462 | 0.83 | METTL3 (0.41) | EGFRABL1ABL2IGF1RRIPK2 | |
| SCHEMBL25048517 | 0.82 | ABL1 (0.40) | EGFRABL1ABL2IGF1RRIPK2 | |
| SCHEMBL31618069 | 0.76 | METTL3 (0.50) | PRMT5METTL3 | |
| SCHEMBL25048766 | 0.76 | METTL3 (0.50) | PRMT5METTL3 | |
| SCHEMBL25047780 | 0.75 | METTL3 (0.51) | PRMT5METTL3 | |
| SCHEMBL30941259 | 0.75 | METTL3 (0.51) | PRMT5METTL3 | |
| SCHEMBL25047923 | 0.74 | ABL1 (0.41) | EGFRABL1ABL2IGF1RRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |