Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.40 |
| ▸ | ACACA | Q13085 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046748 | 0.84 | METTL3 (0.41) | ACACBACACAADORA2AADORA2BADORA1 | |
| SCHEMBL25048408 | 0.83 | ACACB (0.35) | ACACBACACADRD2ADORA2AADORA2B | |
| SCHEMBL25047651 | 0.80 | ACACB (0.39) | ACACBACACACKS1BSKP1SKP2 | |
| SCHEMBL30940981 | 0.78 | ADORA2A (0.30) | ADORA2AADORA2BADORA1 | |
| SCHEMBL25046723 | 0.77 | ACACB (0.42) | ACACBACACADRD2ADORA2AADORA2B | |
| SCHEMBL25049178 | 0.76 | IGF1R (0.45) | — | |
| SCHEMBL25048775 | 0.74 | ACACB (0.39) | ACACBACACADRD2SUV39H2CKS1B | |
| SCHEMBL25046730 | 0.72 | IGF1R (0.41) | — | |
| SCHEMBL25047660 | 0.71 | IGF1R (0.41) | — | |
| SCHEMBL25047546 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |