Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 5/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047651 | 0.84 | ACACB (0.39) | ACACBACACAIGF1RSRC | |
| SCHEMBL25047720 | 0.83 | ACACB (0.40) | ACACBACACASUV39H2PBKADORA2A | |
| SCHEMBL25046748 | 0.82 | METTL3 (0.41) | ACACBACACASUV39H2ADORA2AADORA2B | |
| SCHEMBL25047634 | 0.81 | ADK (0.39) | IGF1RADKFGFR1FGFR4SRC | |
| SCHEMBL30941177 | 0.81 | ADK (0.33) | ADK | |
| SCHEMBL25048941 | 0.77 | SRC (0.38) | FGFR1FGFR4SRC | |
| SCHEMBL25046723 | 0.73 | ACACB (0.42) | ACACBACACASUV39H2PBKADORA2A | |
| SCHEMBL25049143 | 0.73 | ACACB (0.39) | ACACBACACASUV39H2JAK1DRD2 | |
| SCHEMBL25049178 | 0.72 | IGF1R (0.45) | IGF1RSRC | |
| SCHEMBL25048615 | 0.72 | ADK (0.37) | ADKFGFR1FGFR4SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |