Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 11/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047720 | 0.84 | ACACB (0.40) | SUV39H2ACACBACACAADORA2AADORA2B | |
| SCHEMBL25048408 | 0.82 | ACACB (0.35) | SUV39H2ACACBACACAADORA2AADORA2B | |
| SCHEMBL25048354 | 0.82 | METTL3 (0.38) | METTL3PRMT5WDR77 | |
| SCHEMBL31617962 | 0.80 | METTL3 (0.38) | METTL3PRMT5WDR77 | |
| SCHEMBL25047651 | 0.80 | ACACB (0.39) | ACACBACACA | |
| SCHEMBL25046723 | 0.72 | ACACB (0.42) | SUV39H2ACACBACACAADORA2AADORA2B | |
| SCHEMBL25047967 | 0.71 | PRMT5 (0.43) | METTL3PRMT5WDR77 | |
| SCHEMBL31618005 | 0.71 | ALDH1A1 (0.34) | METTL3PRMT5WDR77ACACBACACA | |
| SCHEMBL25049178 | 0.71 | IGF1R (0.45) | — | |
| SCHEMBL25048420 | 0.71 | METTL3 (0.38) | METTL3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |